The Peripheral Cannabinoid Receptor Type 1 (CB1) as a Molecular Target for Modulating Body Weight in Man
SE O'Sullivan, AS Yates, RK Porter - Molecules, 2021 - mdpi.com
The cannabinoid 1 (CB1) receptor regulates appetite and body weight; however, unwanted
central side effects of both agonists (in wasting disorders) or antagonists (in obesity and …
central side effects of both agonists (in wasting disorders) or antagonists (in obesity and …
Gut Probiotics and Health of Dogs and Cats: Benefits, Applications, and Underlying Mechanisms
Q Yang, Z Wu - Microorganisms, 2023 - mdpi.com
Pets (mostly domestic dogs and cats) play an important role in the daily lives of humans and
their health has attracted growing attention from pet owners. The intestinal microbiota, a …
their health has attracted growing attention from pet owners. The intestinal microbiota, a …
Cannabinoid CB2 receptor orthologues; in vitro function and perspectives for preclinical to clinical translation
ER Carruthers, NL Grimsey - British Journal of Pharmacology, 2024 - Wiley Online Library
Cannabinoid CB2 receptor agonists are in development as therapeutic agents, including for
immune modulation and pain relief. Despite promising results in rodent preclinical studies …
immune modulation and pain relief. Despite promising results in rodent preclinical studies …
The emerging role of the endocannabinoidome-gut microbiome axis in eating disorders
HD Mir, G Giorgini, V Di Marzo - Psychoneuroendocrinology, 2023 - Elsevier
Among the sources of chemical signals regulating food intake, energy metabolism and body
weight, few have attracted recently as much attention as the expanded endocannabinoid …
weight, few have attracted recently as much attention as the expanded endocannabinoid …
Engineered Lactobacillus paracasei Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice
Palmitoylethanolamide (PEA) is an N-acylethanolamide produced on-demand by the
enzyme N-acylphosphatidylethanolamine-preferring phospholipase D (NAPE-PLD). Being a …
enzyme N-acylphosphatidylethanolamine-preferring phospholipase D (NAPE-PLD). Being a …
Mutual links between the endocannabinoidome and the gut microbiome, with special reference to companion animals: A nutritional viewpoint
A Schiano Moriello, V Di Marzo, S Petrosino - Animals, 2022 - mdpi.com
Simple Summary Dysbiosis, which is an imbalance of gut microbial composition and
function, can be caused by several external as well as internal factors, contributing to the …
function, can be caused by several external as well as internal factors, contributing to the …
Rapid resolution of large bowel diarrhea after the administration of a combination of a high-fiber diet and a probiotic mixture in 30 dogs
Canine fiber responsive diarrhea is a form of chronic colitis that improves clinically after
adding fiber to the diet. In the present study, we investigated the effect of a combination of a …
adding fiber to the diet. In the present study, we investigated the effect of a combination of a …
Electroacupuncture repairs intestinal barrier by upregulating CB1 through gut microbiota in DSS-induced acute colitis
J Yang, L Wang, M Mei, J Guo, X Yang, S Liu - Chinese medicine, 2023 - Springer
Background A few studies have reported that electroacupuncture (EA) can repair the
intestinal barrier through unknown mechanisms. Cannabinoid receptor 1 (CB1) was shown …
intestinal barrier through unknown mechanisms. Cannabinoid receptor 1 (CB1) was shown …
[引用][C] Goods and bads of the endocannabinoid system as a therapeutic target: Lessons learned after 30 years
Chronic pain in dogs and cats: Is there place for dietary intervention with micro-palmitoylethanolamide?
G Della Rocca, D Gamba - Animals, 2021 - mdpi.com
Simple Summary Chronic pain is being increasingly recognized and addressed in small
animal practice. The recent recognition that inability to communicate does not negate the …
animal practice. The recent recognition that inability to communicate does not negate the …