Spike timing-dependent plasticity and memory

D Debanne, Y Inglebert - Current Opinion in Neurobiology, 2023 - Elsevier
Spike timing-dependent plasticity (STDP) is a bidirectional form of synaptic plasticity
discovered about 30 years ago and based on the relative timing of pre-and post-synaptic …

Regulation of AMPAR trafficking in synaptic plasticity by BDNF and the impact of neurodegenerative disease

J Keifer - Journal of Neuroscience Research, 2022 - Wiley Online Library
Research demonstrates that the neural mechanisms underlying synaptic plasticity and
learning and memory involve mobilization of AMPA‐type neurotransmitter receptors at …

Role of group I metabotropic glutamate receptors in spike timing-dependent plasticity

I Martínez-Gallego, A Rodríguez-Moreno… - International Journal of …, 2022 - mdpi.com
Metabotropic glutamate receptors (mGluRs) are G-protein-coupled receptors that exhibit
enormous diversity in their expression patterns, sequence homology, pharmacology …

Bidirectional regulation of hippocampal synaptic plasticity and modulation of cumulative spatial memory by dopamine D2-like receptors

VM Caragea, D Manahan-Vaughan - Frontiers in behavioral …, 2022 - frontiersin.org
Dopamine is a key factor in the enablement of cognition and hippocampal information
processing. Its action in the hippocampus is mediated by D1/D5 and D2-like (D2, D3, D4) …

Synaptopodin: a key regulator of Hebbian plasticity

PY Wu, Y Inglebert, RA McKinney - Frontiers in Cellular …, 2024 - frontiersin.org
Synaptopodin, an actin-associated protein found in a subset of dendritic spines in
telencephalic neurons, has been described to influence both functional and morphological …

Properties of GABAergic neurons containing calcium-permeable kainate and AMPA-receptors

VP Zinchenko, AM Kosenkov, SG Gaidin, AI Sergeev… - Life, 2021 - mdpi.com
Calcium-permeable kainate and AMPA receptors (CP-KARs and CP-AMPARs), as well as
NMDARs, play a pivotal role in plasticity and in regulating neurotransmitter release. Here we …

Distinct GABAergic modulation of timing-dependent LTP in CA1 pyramidal neurons along the longitudinal axis of the mouse hippocampus

B Khodaie, E Edelmann, V Leßmann - Iscience, 2024 - cell.com
Synaptic plasticity in the hippocampus underlies episodic memory formation, with dorsal
hippocampus being instrumental for spatial memory whereas ventral hippocampus is crucial …

Apoptosis signal-regulating kinase 1 (Ask1) deficiency alleviates MPP+-induced impairment of evoked dopamine release in the mouse hippocampus

F Zhao, C Li, Y Zhuang, Y Yan, Y Gao… - Frontiers in Cellular …, 2024 - frontiersin.org
The dopaminergic system is susceptible to dysfunction in numerous neurological diseases,
including Parkinson's disease (PD). In addition to motor symptoms, some PD patients may …

Synaptic plasticity through a naturalistic lens

C Piette, N Gervasi, L Venance - Frontiers in Synaptic Neuroscience, 2023 - frontiersin.org
From the myriad of studies on neuronal plasticity, investigating its underlying molecular
mechanisms up to its behavioral relevance, a very complex landscape has emerged. Recent …

A soma‐synapses neuron model and FPGA implementation

Z Wang, N Yu, F Essaf - Concurrency and Computation …, 2023 - Wiley Online Library
The neuron model serves as the foundation for building a neural network. The goal of
neuron modeling is to shoot a tradeoff between the biological meaningful and the …