Improving antibody language models with native pairing
SM Burbach, B Briney - Patterns, 2024 - cell.com
Existing antibody language models are limited by their use of unpaired antibody sequence
data. A recently published dataset of∼ 1.6× 10 6 natively paired human antibody sequences …
data. A recently published dataset of∼ 1.6× 10 6 natively paired human antibody sequences …
Innovations and trends in antibody repertoire analysis
DR Townsend, DM Towers, JJ Lavinder… - Current Opinion in …, 2024 - Elsevier
Highlights•Functional screens integrate with single cell BCR-sequencing and
transcriptomics.•Bottom-up and top-down MS enable comprehensive profiling of circulating …
transcriptomics.•Bottom-up and top-down MS enable comprehensive profiling of circulating …
Engineered Multivalent Nanobodies Efficiently Neutralize SARS-CoV-2 Omicron Subvariants BA. 1, BA. 4/5, XBB. 1 and BQ. 1.1
J Wang, B Shi, H Chen, M Yu, P Wang, Z Qian, K Hu… - Vaccines, 2024 - mdpi.com
Most available neutralizing antibodies are ineffective against highly mutated SARS-CoV-2
Omicron subvariants. Therefore, it is crucial to develop potent and broad-spectrum …
Omicron subvariants. Therefore, it is crucial to develop potent and broad-spectrum …