V Bondarenko, Q Chen, TS Tillman, Y Xu… - ACS chemical …, 2024 - ACS Publications
PDZ domains are modular domains that conventionally bind to C terminal or internal motifs of target proteins to control cellular functions through the regulation of protein complex …
J Rosas-García, AJ Padilla-Zúñiga… - Journal of Leukocyte …, 2024 - academic.oup.com
Abstract PDZ (PSD-95/Dlg/ZO-1) domain-containing proteins constitute a large family of scaffolds involved in a wide range of cellular tasks, and mainly studied in polarity functions …
V Young, B Dohai, TCA Hitch, P Hyden, B Weller… - bioRxiv, 2023 - biorxiv.org
The molecular mechanisms by which the gut microbiome influences human health remain largely unknown. Pseudomonadota is the third most abundant phylum in normal gut …
Anomalies in protein–protein interactions may lead to a diseased state, as many cellular functions are sustained by such interactions. These abnormal situations usually arise when …
El estudio de las proteínas se ha estado enfocado a analizar polipéptidos estables y plegados con estructuras bien definidas. Una característica recurrente de tales polipéptidos …
Wnt signaling is a critical and evolutionarily conserved pathway involved in a wide range of biological processes, such as cell development, differentiation, and tissue homeostasis …
Epithelial cells are asymmetrically organized, and their polarization is reliant on the presence of cell junctions. However, this organization is frequently altered in carcinomas …