CD41-deficient exosomes from non-traumatic femoral head necrosis tissues impair osteogenic differentiation and migration of mesenchymal stem cells

W Zhu, MK Guo, W Yang, M Tang, T Chen, D Gan… - Cell death & …, 2020 - nature.com
Non-traumatic osteonecrosis of the femoral head (ONFH) is clinically a devastating and
progressive disease without an effective treatment. Mesenchymal stem cells (MSCs) …

Pathological mechanisms and related markers of steroid-induced osteonecrosis of the femoral head

L Li, S Zhao, Z Leng, S Chen, Y Shi, L Shi, J Li… - Annals of …, 2024 - Taylor & Francis
Background Osteonecrosis of the femoral head (ONFH) is a refractory orthopedic disease
with a high disability rate. Long-term administration of steroids is the most common …

Mesenchymal stem cells‐derived and siRNAs‐encapsulated exosomes inhibit osteonecrosis of the femoral head

C Zhang, Y Su, H Ding, J Yin, Z Zhu… - Journal of Cellular and …, 2020 - Wiley Online Library
Osteonecrosis of the femoral head (ONFH) is a progressive, obstinate and disabling
disease. At present, the treatment of ONFH is still a global medical problem. We aim to …

The Antagonism of neuropeptide Y type I receptor (Y1R) reserves the viability of bone marrow stromal cells in the milieu of osteonecrosis of femoral head (ONFH)

JY Ko, FS Wang, SH Chen, RW Wu, CC Hsu, SJ Kuo - Biomedicines, 2022 - mdpi.com
Neuropeptide Y (NPY)-Y1 receptor (Y1R) signaling is known to negatively affect bone
anabolism. Our study aimed at investigating the impact of NPY-Y1R signaling in the …

Bone biochemical markers, bone mineral density, and the risk of osteonecrosis of the femoral head: a Mendelian randomization study

H Jia, Z Tian, X Liang, H Li, B Lu, J Zhang… - BMC Musculoskeletal …, 2024 - Springer
Alterations in bone metabolism may play a significant role in the early stages of femoral
head necrosis, yet the causal relationship remains unclear. This study utilizes a two-sample …

Osteogenesis-Related Long Noncoding RNA GAS5 as a novel biomarker for osteonecrosis of femoral head

G Liu, S Luo, Y Lei, M Jiao, R Cao, H Guan… - Frontiers in Cell and …, 2022 - frontiersin.org
Background: The lack of effective biomarkers makes it difficult to achieve early diagnosis
and intervention for osteonecrosis of the femoral head (ONFH). Hence, we aimed to identify …

[HTML][HTML] Остеонекроз головки бедренной кости, не связанный с травмой: хирургические и консервативные методы лечения (часть 2)

НА Шостак, АА Клименко, НА Демидова… - Лечебное …, 2021 - cyberleninka.ru
Остеонекроз–состояние, обусловленное различными заболеваниями и трудно
поддающееся лечению, при этом патогенетические механизмы его развития …

MicroRNA-29a Mitigates Laminectomy-Induced Spinal Epidural Fibrosis and Gait Dysregulation by Repressing TGF-β1 and IL-6

IT Lin, YH Lin, WS Lian, FS Wang, RW Wu - International Journal of …, 2023 - mdpi.com
Spinal epidural fibrosis is one of the typical features attributable to failed back surgery
syndrome, with excessive scar development in the dura and nerve roots. The microRNA-29 …

[HTML][HTML] 酒精性股骨头坏死发病机制和基因学研究进展

伟陈, 黎明卿, 攀峰吴, 举玉唐 - Chinese Journal of Reparative and …, 2022 - ncbi.nlm.nih.gov
酒精性股骨头坏死发病机制和基因学研究进展- PMC Back to Top Skip to main content NIH NLM
Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation …

Hyperbaric Oxygen Therapy for the Treatment of Bone-Related Diseases

J Feng, C Zhu, J Zou, L Zhang - International Journal of Molecular …, 2025 - mdpi.com
Hyperbaric oxygen therapy (HBOT) is a therapeutic modality that enhances tissue
oxygenation by delivering 100% oxygen at pressures greater than 1 absolute atmosphere …