Homology modeling is one of the computational structure prediction methods that are used
to determine protein 3D structure from its amino acid sequence. It is considered to be the …

Zika virus (ZIKV) remained largely quiescent for nearly six decades after its first appearance
in 1947. ZIKV reappeared after 2007, resulting in a declaration of an international “public …

Evidence of male-to-female sexual transmission of Zika virus (ZIKV) and viral RNA in semen
and sperm months after infection supports a potential role for testicular cells in ZIKV …

Zika virus (ZIKV) remains a potentially significant public health concern because it can
cause teratogenic effects, such as microcephaly in newborns and neurological disease, like …

Over recent years, many outbreaks caused by (re) emerging RNA viruses have been
reported worldwide, including life-threatening Flaviviruses, such as Dengue (DENV) and …

RNA methyltransferases (MTases) are ubiquitous enzymes whose hitherto low profile in
medicinal chemistry, contrasts with the surging interest in RNA methylation, the arguably …

Highlights•Recent advances in Zika virus drug discovery efforts.•Drug repositioning and
computationally guided compounds.•New inhibitors and promising ZIKV molecular …

Molecular docking has been developed and improving for many years, but its ability to bring
a medicine to the drug market effectively is still generally questioned. In this chapter, we …

In recent years, the outbreak of infectious disease caused by Zika virus (ZIKV) has posed a
major threat to global public health, calling for the development of therapeutics to treat ZIKV …

Zika virus (ZIKV), an emerging arbovirus, has become a major human health concern
globally due to its association with congenital abnormalities and neurological diseases …