Nitrile-containing pharmaceuticals: efficacious roles of the nitrile pharmacophore

FF Fleming, L Yao, PC Ravikumar, L Funk… - Journal of medicinal …, 2010 - ACS Publications
Over 30 nitrile-containing pharmaceuticals are prescribed for a diverse variety of medicinal
indications with more than 20 additional nitrile-containing leads in clinical development …

Recent advances in the chemistry and biology of benzothiazoles

RK Gill, RK Rawal, J Bariwal - Archiv der Pharmazie, 2015 - Wiley Online Library
Benzothiazole is a privileged heterocyclic scaffold having a benzene ring fused with a five‐
membered thiazole ring. This moiety has attracted considerable attention because of its …

Photodegradation characteristics of PPCPs in water with UV treatment

I Kim, H Tanaka - Environment international, 2009 - Elsevier
The degradation characteristics of PPCPs commonly found in surface water under UV
treatment were examined for 30 kinds of PPCPs using a UV/Lamp1 that emits light at a …

Antifungal Activity of Endophytic Aspergillus terreus Extract Against Some Fungi Causing Mucormycosis: Ultrastructural Study

AH Hashem, AM Shehabeldine, AM Abdelaziz… - Applied Biochemistry …, 2022 - Springer
Endophytes fungi are applied as favorable safe antifungal agents as well as natural
bioactive compounds reservoir. In the current study, the inhibitory effect of endophytic fungus …

Heterogeneous photocatalytic studies of analgesic and non-steroidal anti-inflammatory drugs

A Kaur, A Umar, SK Kansal - Applied Catalysis A: General, 2016 - Elsevier
The presence of pharmaceutical compounds in natural water is considered as an
environmental problem due to their regular input in aquatic system and hence their removal …

[HTML][HTML] Extraction and characterization of gelatin from camel skin (potential halal gelatin) and production of gelatin nanoparticles

MA Ahmed, HA Al-Kahtani, I Jaswir… - Saudi Journal of …, 2020 - Elsevier
Gelatin is used as an ingredient in both food and non-food industries as a gelling agent,
stabilizer, thickener, emulsifier, and film former. Porcine skins, bovine hides, and cattle …

Networks for systems biology: conceptual connection of data and function

F Emmert-Streib, M Dehmer - IET systems biology, 2011 - IET
The purpose of this study is to survey the use of networks and network-based methods in
systems biology. This study starts with an introduction to graph theory and basic measures …

Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole

S Hengsawas Surasarang, JM Keen… - Drug development …, 2017 - Taylor & Francis
The purpose of this study was to enhance the dissolution properties of albendazole (ABZ) by
the use of amorphous solid dispersions. Phase diagrams of ABZ–polymer binary mixtures …

Molecular clip and tweezer introduce new mechanisms of enzyme inhibition

P Talbiersky, F Bastkowski, FG Klärner… - Journal of the …, 2008 - ACS Publications
Artificial molecular clips and tweezers, designed for cofactor and amino acid recognition, are
able to inhibit the enzymatic activity of alcohol dehydrogenase (ADH). IC50 values and …

Detection of bacterial spores with Lanthanide− Macrocycle binary complexes

ML Cable, JP Kirby, DJ Levine, MJ Manary… - Journal of the …, 2009 - ACS Publications
The detection of bacterial spores via dipicolinate-triggered lanthanide luminescence has
been improved in terms of detection limit, stability, and susceptibility to interferents by use of …