Vagus nerve stimulation (VNS) is a promising therapy for treatment of various conditions that
are resistant to standard medication, such as heart failure, epilepsy, and depression. The …

The move from the concept of homeostasis to that of allostasis has led reactivity stress
research to widen the object of its investigation: from the brief physiological response that …

Bioelectronic therapies modulating the vagus nerve are promising for cardiovascular,
inflammatory, and mental disorders. Clinical applications are however limited by side-effects …

Objective. Given current clinical interest in vagus nerve stimulation (VNS), there are
surprisingly few studies characterizing the anatomy of the vagus nerve in large animal …

Electrical stimulation of the cervical vagus nerve using implanted electrodes (VNS) is FDA-
approved for the treatment of drug-resistant epilepsy, treatment-resistant depression, and …

Introduction Despite detailed characterization of fascicular organization of somatic nerves,
the functional anatomy of fascicles evident in human and large mammal cervical vagus …

Background Due to the lack of understanding of the fascicular organisation, vagus nerve
stimulation (VNS) leads to unwanted off-target effects. Micro-computed tomography …

The adaptability of the central nervous system has been revealed in several model systems.
Of particular interest to central nervous system-injured individuals is the ability for neural …

Despite detailed characterization of fascicular organization of somatic nerves, the functional
anatomy of fascicles evident in human and large mammal cervical vagus nerve is unknown …

Background: Previous research has revealed the logical mapping of fascicles in both human
somatic and pig vagus nerves, but the organization of fascicles within the human vagus …