Hydrogenases
The reaction takes place at a specialized metal center that dramatically increases the acidity
of H2 and leads to a heterolytic splitting of the molecule which is strongly accelerated by the …
of H2 and leads to a heterolytic splitting of the molecule which is strongly accelerated by the …
[HTML][HTML] [NiFe] hydrogenases: a common active site for hydrogen metabolism under diverse conditions
Hydrogenase proteins catalyze the reversible conversion of molecular hydrogen to protons
and electrons. The most abundant hydrogenases contain a [NiFe] active site; these proteins …
and electrons. The most abundant hydrogenases contain a [NiFe] active site; these proteins …
Current state of [FeFe]-hydrogenase research: biodiversity and spectroscopic investigations
Hydrogenases are redox enzymes that catalyze the conversion of protons and molecular
hydrogen (H2). Based on the composition of the active site cofactor, the monometallic [Fe] …
hydrogen (H2). Based on the composition of the active site cofactor, the monometallic [Fe] …
Structure, function and biosynthesis of O2-tolerant hydrogenases
J Fritsch, O Lenz, B Friedrich - Nature Reviews Microbiology, 2013 - nature.com
Molecular hydrogen (H2) is used as an energy source or a way to deposit excess reducing
power by a wide range of microorganisms. Both H2 oxidation and production are catalysed …
power by a wide range of microorganisms. Both H2 oxidation and production are catalysed …
Catalytic Production of Hydrogen Peroxide and Water by Oxygen-Tolerant [NiFe]-Hydrogenase during H2 Cycling in the Presence of O2
L Lauterbach, O Lenz - Journal of the American Chemical Society, 2013 - ACS Publications
Hydrogenases control the H2-related metabolism in many microbes. Most of these enzymes
are prone to immediate inactivation by O2. However, a few members of the subclass of …
are prone to immediate inactivation by O2. However, a few members of the subclass of …
Principles of sustained enzymatic hydrogen oxidation in the presence of oxygen–the crucial influence of high potential Fe–S clusters in the electron relay of [NiFe] …
“Hyd-1”, produced by Escherichia coli, exemplifies a special class of [NiFe]-hydrogenase
that can sustain high catalytic H2 oxidation activity in the presence of O2 an intruder that …
that can sustain high catalytic H2 oxidation activity in the presence of O2 an intruder that …
EPR Spectroscopic Studies of the Fe–S Clusters in the O2-Tolerant [NiFe]-Hydrogenase Hyd-1 from Escherichia coli and Characterization of the Unique [4Fe–3S] …
The unusual [4Fe–3S] cluster proximal to the active site plays a crucial role in allowing a
class of [NiFe]-hydrogenases to function in the presence of O2 through its unique ability to …
class of [NiFe]-hydrogenases to function in the presence of O2 through its unique ability to …
Proton transfer in the catalytic cycle of [NiFe] hydrogenases: insight from vibrational spectroscopy
PA Ash, R Hidalgo, KA Vincent - ACS catalysis, 2017 - ACS Publications
Catalysis of H2 production and oxidation reactions is critical in renewable energy systems
based around H2 as a clean fuel, but the present reliance on platinum-based catalysts is not …
based around H2 as a clean fuel, but the present reliance on platinum-based catalysts is not …
H2‐driven cofactor regeneration with NAD(P)+‐reducing hydrogenases
L Lauterbach, O Lenz, KA Vincent - The FEBS journal, 2013 - Wiley Online Library
A large number of industrially relevant enzymes depend upon nicotinamide cofactors, which
are too expensive to be added in stoichiometric amounts. Existing NAD (P) H‐recycling …
are too expensive to be added in stoichiometric amounts. Existing NAD (P) H‐recycling …
The [NiFe]-Hydrogenase of the Cyanobacterium Synechocystis sp. PCC 6803 Works Bidirectionally with a Bias to H2 Production
CL McIntosh, F Germer, R Schulz, J Appel… - Journal of the …, 2011 - ACS Publications
Protein film electrochemistry (PFE) was utilized to characterize the catalytic activity and
oxidative inactivation of a bidirectional [NiFe]-hydrogenase (HoxEFUYH) from the …
oxidative inactivation of a bidirectional [NiFe]-hydrogenase (HoxEFUYH) from the …