Optical mapping (OM) provides single-molecule readouts of fluorescently labeled sequence motifs on long fragments of DNA, resolved to nucleotide-level coordinates. With the advent …
Genome wide optical maps are high resolution restriction maps that give a unique numeric representation to a genome. They are produced by assembling hundreds of thousands of …
P Stawczyk, R Nowak - arXiv preprint arXiv:2210.06865, 2022 - arxiv.org
Reducing the cost of sequencing genomes provided by next-generation sequencing technologies has greatly increased the number of genomic projects. As a result, there is a …
Though genome analysis is used in other places, understanding the effects genes have on humans is arguably its most significant use. A fundamental roadblock to genome analysis is …
K Mukherjee, D Dole-Muinos, M Rossi… - IEEE/ACM …, 2021 - ieeexplore.ieee.org
Optical mapping is a method for creating high resolution restriction maps of an entire genome. Optical mapping has been largely automated, and first produces single molecule …
K Mukherjee, M Rossi, D Dole-Muinos, A Ajayi… - bioRxiv, 2021 - biorxiv.org
Optical mapping is a method for creating high resolution restriction maps of an entire genome. Optical mapping has been largely automated, and first produces single molecule …