[HTML][HTML] Advances in optical mapping for genomic research

Y Yuan, CYL Chung, TF Chan - Computational and Structural …, 2020 - Elsevier
Recent advances in optical mapping have allowed the construction of improved genome
assemblies with greater contiguity. Optical mapping also enables genome comparison and …

FaNDOM: Fast nested distance-based seeding of optical maps

SR Dehkordi, J Luebeck, V Bafna - Patterns, 2021 - cell.com
Optical mapping (OM) provides single-molecule readouts of fluorescently labeled sequence
motifs on long fragments of DNA, resolved to nucleotide-level coordinates. With the advent …

Fast and efficient Rmap assembly using the Bi-labelled de Bruijn graph

K Mukherjee, M Rossi, L Salmela… - Algorithms for Molecular …, 2021 - Springer
Genome wide optical maps are high resolution restriction maps that give a unique numeric
representation to a genome. They are produced by assembling hundreds of thousands of …

Fast genomic optical map assembly algorithm using binary representation

P Stawczyk, R Nowak - arXiv preprint arXiv:2210.06865, 2022 - arxiv.org
Reducing the cost of sequencing genomes provided by next-generation sequencing
technologies has greatly increased the number of genomic projects. As a result, there is a …

[PDF][PDF] Improving Contiguity and Accuracy in Genome Assembly.

R Walve - 2023 - helda.helsinki.fi
Though genome analysis is used in other places, understanding the effects genes have on
humans is arguably its most significant use. A fundamental roadblock to genome analysis is …

Finding Overlapping Rmaps via Clustering

K Mukherjee, D Dole-Muinos, M Rossi… - IEEE/ACM …, 2021 - ieeexplore.ieee.org
Optical mapping is a method for creating high resolution restriction maps of an entire
genome. Optical mapping has been largely automated, and first produces single molecule …

Finding Overlapping Rmaps via Gaussian Mixture Model Clustering

K Mukherjee, M Rossi, D Dole-Muinos, A Ajayi… - bioRxiv, 2021 - biorxiv.org
Optical mapping is a method for creating high resolution restriction maps of an entire
genome. Optical mapping has been largely automated, and first produces single molecule …