[HTML][HTML] Baicalin and baicalein in modulating tumor microenvironment for cancer treatment: a comprehensive review with future perspectives

R Wang, C Wang, L Lu, F Yuan, F He - Pharmacological Research, 2024 - Elsevier
Cancer is a leading cause of death worldwide. The burden of cancer incidence and mortality
is increasing rapidly. New approaches to cancer prevention and treatment are urgently …

Baicalin mediated regulation of key signaling pathways in cancer

S Singh, A Meena, S Luqman - Pharmacological research, 2021 - Elsevier
Baicalin has been widely investigated against different types of malignancies both at the
cellular and molecular levels over the past few years. Due to its remarkable anti-proliferative …

Applications, phytochemistry, pharmacological effects, pharmacokinetics, toxicity of Scutellaria baicalensis Georgi. and its probably potential therapeutic effects on …

JW Song, JY Long, L Xie, LL Zhang, QX Xie, HJ Chen… - Chinese Medicine, 2020 - Springer
Scutellaria baicalensis Georgi.(SB) is a common heat-clearing medicine in traditional
Chinese medicine (TCM). It has been used for thousands of years in China and its …

Comparative metabolomics of flavonoids in twenty vegetables reveal their nutritional diversity and potential health benefits

H Tao, Y Zhao, L Li, Y He, X Zhang, Y Zhu… - Food Research …, 2023 - Elsevier
Vegetables are rich in flavonoids and are widely consumed in our daily life. However,
comprehensive information on flavonoids components in vegetable varieties and the …

Advances in Anti-Cancer Activities of Flavonoids in Scutellariae radix: Perspectives on Mechanism

Y Gu, QI Zheng, G Fan, R Liu - International Journal of Molecular …, 2022 - mdpi.com
Despite encouraging progresses in the development of novel therapies, cancer remains the
dominant cause of disease-related mortality and has become a leading economic and …

A comprehensive review of natural flavonoids with anti-SARS-CoV-2 activity

JY Yang, YX Ma, Y Liu, XJ Peng, XZ Chen - Molecules, 2023 - mdpi.com
The COVID-19 pandemic caused by SARS-CoV-2 has majorly impacted public health and
economies worldwide. Although several effective vaccines and drugs are now used to …

Latest research progress on anticancer effect of baicalin and its aglycone baicalein

L Wang, T Feng, Z Su, C Pi, Y Wei, L Zhao - Archives of Pharmacal …, 2022 - Springer
Cancer, which is a leading cause of deaths around the world, is characterized by genetic
mutations and epigenetic changes. Baicalin and its aglycone baicalein, the major bioactive …

[HTML][HTML] Myc oncogene: a druggable target for treating cancers with natural products

KI Chan, S Zhang, G Li, Y Xu, L Cui, Y Wang… - Aging and …, 2024 - ncbi.nlm.nih.gov
Various diseases, including cancers, age-associated disorders, and acute liver failure, have
been linked to the oncogene, MYC. Animal testing and clinical trials have shown that …

Baicalin ameliorates Mycoplasma gallisepticum-induced lung inflammation in chicken by inhibiting TLR6-mediated NF-κB signalling

M Zou, L Yang, L Niu, Y Zhao, Y Sun, Y Fu… - British Poultry …, 2021 - Taylor & Francis
Mycoplasma gallisepticum (MG) causes severe lung inflammation and cell damage by
activating toll-like receptor (TLR) signalling, the nuclear factor-kappaB (NF-κ B) pathway and …

Investigation of the ameliorative effects of baicalin against arsenic trioxide-induced cardiac toxicity in mice

X Sun, X Wang, Q He, M Zhang, L Chu, Y Zhao… - International …, 2021 - Elsevier
Baicalin (BA), a kind of flavonoids compound, comes from Scutellaria baicalensis Georgi (a
kind of perennial herb) and has beneficial effects on the cardiovascular system through anti …