Nanoparticle contrast agents for computed tomography: a focus on micelles

DP Cormode, PC Naha… - Contrast media & …, 2014 - Wiley Online Library
Computed tomography (CT) is an X‐ray‐based whole‐body imaging technique that is
widely used in medicine. Clinically approved contrast agents for CT are iodinated small …

Cell encapsulation: Overcoming barriers in cell transplantation in diabetes and beyond

M Farina, JF Alexander, U Thekkedath, M Ferrari… - Advanced drug delivery …, 2019 - Elsevier
Cell-based therapy is emerging as a promising strategy for treating a wide range of human
diseases, such as diabetes, blood disorders, acute liver failure, spinal cord injury, and …

Microcapsules and microcarriers for in situ cell delivery

RM Hernández, G Orive, A Murua, JL Pedraz - Advanced drug delivery …, 2010 - Elsevier
In recent years, the use of transplanted living cells pumping out active factors directly at the
site has proven to be an emergent technology. However a recurring impediment to rapid …

Cell microencapsulation technology: towards clinical application

A Murua, A Portero, G Orive, RM Hernández… - Journal of controlled …, 2008 - Elsevier
The pharmacokinetic properties of a drug can be significantly improved by the delivery
process. Scientists have understood that developing suitable drug delivery systems that …

Alginate macroencapsulation of pig islets allows correction of streptozotocin-induced diabetes in primates up to 6 months without immunosuppression

D Dufrane, RM Goebbels, P Gianello - Transplantation, 2010 - journals.lww.com
Background. This study assessed the capacity of alginate-encapsulated islets to reverse
diabetes in a pig-to-primate model. Methods. Adult pig islets were encapsulated in …

[HTML][HTML] Cell microencapsulation technologies for sustained drug delivery: Latest advances in efficacy and biosafety

TB Lopez-Mendez, E Santos-Vizcaino… - Journal of Controlled …, 2021 - Elsevier
The development of cell microencapsulation systems began several decades ago. However,
today few systems have been tested in clinical trials. For this reason, in the last years …

Inorganic nanoparticles based contrast agents for X‐ray computed tomography

A Jakhmola, N Anton… - Advanced healthcare …, 2012 - Wiley Online Library
Nanomaterials have gained considerable attention and interest in the development of new
and efficient molecular probes for medical diagnosis and imaging. Heavy metal …

MRI-detectable pH nanosensors incorporated into hydrogels for in vivo sensing of transplanted-cell viability

KWY Chan, G Liu, X Song, H Kim, T Yu, DR Arifin… - Nature materials, 2013 - nature.com
Biocompatible nanomaterials and hydrogels have become an important tool for improving
cell-based therapies by promoting cell survival and protecting cell transplants from immune …

Anti-CD4-targeted gold nanoparticles induce specific contrast enhancement of peripheral lymph nodes in X-ray computed tomography of live mice

W Eck, AI Nicholson, H Zentgraf, W Semmler… - Nano …, 2010 - ACS Publications
Antibody-conjugated gold nanoparticles have been applied as a biologically targeted
contrast agent in live mice for one of the most widely used medical imaging methods, X-ray …

[HTML][HTML] Encapsulated islet transplantation: where do we stand?

V Vaithilingam, S Bal, BE Tuch - The review of diabetic studies …, 2017 - ncbi.nlm.nih.gov
Transplantation of pancreatic islets encapsulated within immuno-protective microcapsules is
a strategy that has the potential to overcome graft rejection without the need for toxic …