Butyrate-producing human gut symbiont, Clostridium butyricum, and its role in health and disease

MK Stoeva, J Garcia-So, N Justice, J Myers, S Tyagi… - Gut …, 2021 - Taylor & Francis
Clostridium butyricum is a butyrate-producing human gut symbiont that has been safely
used as a probiotic for decades. C. butyricum strains have been investigated for potential …

Current challenges and best-practice protocols for microbiome analysis

R Bharti, DG Grimm - Briefings in bioinformatics, 2021 - academic.oup.com
Analyzing the microbiome of diverse species and environments using next-generation
sequencing techniques has significantly enhanced our understanding on metabolic …

Ketogenic diet alleviates colitis by reduction of colonic group 3 innate lymphoid cells through altering gut microbiome

C Kong, X Yan, Y Liu, L Huang, Y Zhu, J He… - Signal transduction and …, 2021 - nature.com
Accumulating evidence suggests that ketogenic diets (KDs) mediate the rise of circulating
ketone bodies and exert a potential anti-inflammatory effect; however, the consequences of …

Intestinal epithelial cells: at the interface of the microbiota and mucosal immunity

AT Soderholm, VA Pedicord - Immunology, 2019 - Wiley Online Library
The intestinal epithelium forms a barrier between the microbiota and the rest of the body. In
addition, beyond acting as a physical barrier, the function of intestinal epithelial cells (IEC s) …

Microbial transmission in animal social networks and the social microbiome

A Sarkar, S Harty, KVA Johnson, AH Moeller… - Nature ecology & …, 2020 - nature.com
Host-associated microbiomes play an increasingly appreciated role in animal metabolism,
immunity and health. The microbes in turn depend on their host for resources and can be …

Maternal immune activation induces autism-like changes in behavior, neuroinflammatory profile and gut microbiota in mouse offspring of both sexes

AM Tartaglione, A Villani, MA Ajmone-Cat… - Translational …, 2022 - nature.com
Abstract Autism Spectrum Disorder (ASD) is a sex-biased neurodevelopmental disorder with
a male to female prevalence of 4: 1, characterized by persistent deficits in social …

Emerging concepts in intestinal immune control of obesity-related metabolic disease

S Khan, H Luck, S Winer, DA Winer - Nature Communications, 2021 - nature.com
The intestinal immune system is an important modulator of glucose homeostasis and obesity-
associated insulin resistance. Dietary factors, the intestinal microbiota and their metabolites …

Stochasticity constrained by deterministic effects of diet and age drive rumen microbiome assembly dynamics

O Furman, L Shenhav, G Sasson, F Kokou… - Nature …, 2020 - nature.com
How complex communities assemble through the animal's life, and how predictable the
process is remains unexplored. Here, we investigate the forces that drive the assembly of …

Identification of gut microbial species linked with disease variability in a widely used mouse model of colitis

SC Forster, S Clare, BS Beresford-Jones… - Nature …, 2022 - nature.com
Experimental mouse models are central to basic biomedical research; however, variability
exists across genetically identical mice and mouse facilities making comparisons difficult …

[HTML][HTML] Gut microbiota modulate CD8 T cell responses to influence colitis-associated tumorigenesis

IY Amy, L Zhao, KA Eaton, S Ho, J Chen, S Poe… - Cell reports, 2020 - cell.com
There is increasing evidence that gut microbiome perturbations, also known as dysbiosis,
can influence colorectal cancer development. To understand the mechanisms by which the …