Cell-surface proteins of the tetraspanin family are small, and often hidden by a canopy of tall
glycoprotein neighbours in the cell membrane. Consequently, tetraspanins have been …

Metastatic spread of cancer continues to be the greatest barrier to cancer cure.
Understanding the molecular mechanisms of metastasis is crucial for the design and …

CD82 and CD9 are tetraspanin membrane proteins that can function as suppressors of
tumor metastasis. Expression of CD9 and CD82 in transfected cells strongly suppresses β …

Prostate cancer has the highest prevalence of any nonskin cancer in the human body, with
similar likelihood of neoplastic foci found within the prostates of men around the world …

Tumours progress through a cascade of events that enable the formation of metastases.
Some of the components that are required for this fatal process are well established …

Metastatic cancers adopt certain properties of normal cells in developing or regenerating
organs, such as the ability to proliferate and alter tissue organization. We find here that …

Prostate cancer afflicts one man in nine over the age of 65 and represents the most
frequently diagnosed cancer in American men (Coffey 1993). Early detection through serum …

Serum potentially carries an archive of important histological information whose
determination could serve to improve early disease detection. The analysis of serum …

Glioblastoma multiforme (GBM) is the most aggressive form of brain cancer due to its highly
invasive nature that impedes the surgical removal of all tumor cells, making relapse …

It is now widely accepted that cancer is attributed to the accumulation of genetic alterations
in cells. Thus, to understand the molecular mechanisms of cancer metastasis, it is …