Astaxanthin as a peroxisome proliferator-activated receptor (PPAR) modulator: its therapeutic implications

CI Choi - Marine drugs, 2019 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) are part of the nuclear hormone
receptors superfamily that plays a pivotal role in functions such as glucose and lipid …

Therapeutic potentials of microalgae and their bioactive compounds on diabetes mellitus

K Tamel Selvan, JA Goon, S Makpol, JK Tan - Marine Drugs, 2023 - mdpi.com
Diabetes mellitus is a metabolic disorder characterized by hyperglycemia due to impaired
insulin secretion, insulin resistance, or both. Oxidative stress and chronic low-grade …

Effects of microalgae on metabolic syndrome

K Tamel Selvan, JA Goon, S Makpol, JK Tan - Antioxidants, 2023 - mdpi.com
Metabolic syndrome (MetS) is a cluster of metabolic disturbances, including abdominal
obesity, hypertension, hypertriglyceridemia, reduced high-density lipoprotein cholesterol …

Anthocyanin profiling of maize grains using DIESI-MSQD reveals that cyanidin-based derivatives predominate in purple corn, whereas pelargonidin-based molecules …

HA Peniche-Pavía, A Tiessen - Journal of agricultural and food …, 2020 - ACS Publications
Corn seeds contain natural pigments and antioxidants, such as the molecular variants of
flavonoids and carotenoids. The aleurone and pericarp tissues from pigmented genotypes …

Marine natural and nature-inspired compounds targeting peroxisome proliferator activated receptors (PPARs)

E D'Aniello, P Amodeo, RM Vitale - Marine Drugs, 2023 - mdpi.com
Peroxisome proliferator-activated receptors α, γ and β/δ (PPARα, PPARγ, and PPARβ/δ) are
a family of ligand-activated transcriptional factors belonging to the superfamily of nuclear …

[HTML][HTML] Two antibacterial and PPARα/γ-agonistic unsaturated keto fatty acids from a coral-associated actinomycete of the genus Micrococcus

AR Sharma, E Harunari, N Oku… - Beilstein Journal of …, 2020 - beilstein-journals.org
A pair of geometrically isomeric unsaturated keto fatty acids,(6E, 8Z)-and (6E, 8E)-5-oxo-6, 8-
tetradecadienoic acids (1 and 2), were isolated from the culture broth of an actinomycete of …

Discovery and Anti-Inflammatory Activity of a Cyanobacterial Fatty Acid Targeting the Keap1/Nrf2 Pathway

FH Al-Awadhi, EF Simon, N Liu, R Ratnayake, VJ Paul… - Marine Drugs, 2023 - mdpi.com
The monounsaturated fatty acid 7 (E)-9-keto-hexadec-7-enoic acid (1) and three structurally
related analogues with different oxidation states and degrees of unsaturation (2–4) were …

Metabolite Profile Characterization of Cyanobacterial Strains with Bioactivity on Lipid Metabolism Using In Vivo and In Vitro Approaches

T Ribeiro, K Jónsdóttir, R Hernandez-Bautista… - Marine Drugs, 2023 - mdpi.com
Cyanobacteria have demonstrated their therapeutic potential for many human diseases. In
this work, cyanobacterial extracts were screened for lipid reducing activity in zebrafish larvae …

[HTML][HTML] Synthesis and biological evaluations of marine oxohexadecenoic acids: PPARα/γ dual agonism and anti-diabetic target gene effects

T Sæther, SM Paulsen, JE Tungen, A Vik… - European journal of …, 2018 - Elsevier
Obesity and associated disorders such as metabolic syndrome and type 2 diabetes (T2D)
have reached epidemic proportions. Several natural products have been reported as …

Biological evaluations, NMR analyses, molecular modeling studies, and overview of the synthesis of the marine natural product (−)-mucosin

JMJ Nolsøe, J Underhaug, ÅM Sørskar, SG Antonsen… - Molecules, 2024 - mdpi.com
Natural products obtained from marine organisms continue to be a rich source of novel
structural architecture and of importance in drug discovery, medicine, and health. However …