Factor XIII (FXIII) is a transglutaminase enzyme that catalyses the formation of ε-(γ-glutamyl)
lysyl isopeptide bonds into protein substrates. The plasma form, FXIIIA2B2, has an …

Factor XIII (FXIII) is a multifunctional pro-γ-transglutaminase that, in addition to its well-
known role in hemostasis, has a crucial role in angiogenesis, maintenance of pregnancy …

Inherited deficiency of FXIII A subunit (FXIII-A) is a rare (1: 2,000,000) but very severe
bleeding diathesis. The incidence is much higher in communities where the practice of …

Factor XIII deficiency (FXIIID) is a rare hereditary bleeding disorder arising from
heterogeneous mutations, which can lead to life‐threatening hemorrhage. The diagnosis of …

Factor XIII deficiency (FXIIID) is a rare bleeding disorder with an estimated prevalence of 1 in
2-million population worldwide. In Iran, a Middle Eastern country with a high rate of …

With 473 patients, Iran has about one third of the world's patients with severe congenital
factor XIII (FXIII) deficiency. A considerable number of patients with FXIII deficiency (FXIIID) …

Introduction Intracranial haemorrhage in children with inherited bleeding disorders is a
potentially life‐threatening complication and presents a significant therapeutic challenge …

Objective: To provide a comprehensive literature review on roles of coagulation factor XIII
(FXIII) in coagulation, wound healing, neoplasm, bone metabolism, and pregnancy. Data …

ABSTRACT Background: Rare bleeding disorders (RBDs) are heterogeneous disorders,
mostly inherited in an autosomal recessive pattern. Iran is a Mideast country with a high rate …

Factor XIII (FXIII) deficiency is an extremely rare hemorrhagic disorder with an approximate
worldwide incidence of one per two million. With current tests, diagnosis of this disease can …