Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease that causes
damage to multiple organ systems. Despite decades of research and available murine …

During the last decades, high-throughput assessment of gene expression in patient tissues
using microarray technology or RNA-Seq took center stage in clinical research. Insights into …

Background Coronavirus disease 2019 (COVID-19) is commonly associated with skin
manifestations, and may also exacerbate existing skin diseases, yet the relationship …

Analysis of gene expression from cutaneous lupus erythematosus, psoriasis, atopic
dermatitis, and systemic sclerosis using gene set variation analysis (GSVA) revealed that …

The pathophysiology of cutaneous lupus erythematosus (CLE) encompasses the complex
interactions between genetics, the environment, and cells and their products. Recent data …

Summary Interleukin (IL)‐17 is an emerging target for inflammatory skin disorders. Given the
remarkable success of its therapeutic inhibition in psoriasis, the pathogenic role of this …

Cutaneous lupus erythematosus (CLE) is a disfiguring autoimmune skin disease
characterized by an inflammatory infiltrate rich in T cells, which are strongly implicated in …

Cutaneous lupus erythematosus (CLE) is a common disease that may appear as a separate
entity from systemic lupus erythematosus (SLE), precede SLE development, or occur as a …

MicroRNAs (miRNAs) are endogenous small non-coding RNA molecules that regulate the
gene expression at a post-transcriptional level and participate in maintaining the correct cell …

Cutaneous lupus erythematosus (CLE) is an inflammatory disease with a broad range of
cutaneous manifestations that may be accompanied by systemic symptoms. The …