Ferroptosis, a newly discovered iron-dependent cell death pathway, is characterized by lipid
peroxidation and GSH depletion mediated by iron metabolism and is morphologically …

Ferroptosis, a newform of programmed cell death, driven by peroxidative damages of
polyunsaturated-fatty-acid-containing phospholipids in cellular membranes and is extremely …

Background: Inflammation resolution and cardiac repair initiation after myocardial infarction
(MI) require timely activation of reparative signals. Histone lactylation confers macrophage …

Multi-copper oxidases (MCOs) are a small group of enzymes that oxidize their substrate with
the concomitant reduction of dioxygen to two water molecules. Generally, multi-copper …

Quercetin, a polyphenolic bioflavonoid, possesses multiple pharmacological actions
including anti-inflammatory and antitumor properties. However, the precise action …

Melatonin exhibits anti‐inflammatory and anticancer effects and could be a
chemopreventive and chemotherapeutic agent against cancers, but the precise mechanisms …

The mammalian multicopper ferroxidases (MCFs) ceruloplasmin (CP), hephaestin (HEPH)
and zyklopen (ZP) comprise a family of conserved enzymes that are essential for body iron …

Introduction. The master clock, which is located in the suprachiasmatic nucleus (SCN),
harmonizes clock genes present in the liver to synchronize life rhythms and bioactivity with …

Safe trafficking of iron across the cell membrane is a delicate process that requires specific
protein carriers. While many proteins involved in iron uptake by cells are known, only one …

Abstract Interleukin-1β (IL-1β) belongs to IL-1 family and is a potent pro-inflammatory
cytokine. It is known to be also involved in a variety of cellular activities, including cell …