Recent advances in the treatment of bone metastases and primary bone tumors: An up-to-date review

AE Bădilă, DM Rădulescu, AG Niculescu… - Cancers, 2021 - mdpi.com
Simple Summary Bone represents a common metastatic site for patients with advanced
cancers while also being associated with rare but challenging primary tumors. As the …

[HTML][HTML] Advanced nanoscale drug delivery systems for bone cancer therapy

N Amiryaghoubi, M Fathi, J Barar, H Omidian… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Bone tumors are relatively rare, which are complex cancers and primarily involve the long
bones and pelvis. Bone cancer is mainly categorized into osteosarcoma (OS) …

Meeting contemporary challenges: development of nanomaterials for veterinary medicine

O Danchuk, A Levchenko, R da Silva Mesquita… - Pharmaceutics, 2023 - mdpi.com
In recent decades, nanotechnology has been rapidly advancing in various fields of human
activity, including veterinary medicine. The review presents up-to-date information on recent …

Application of biocompatible drug delivery nanosystems for the treatment of naturally occurring cancer in dogs

N Ambrosio, S Voci, A Gagliardi, E Palma… - Journal of Functional …, 2022 - mdpi.com
Background: Cancer is a common disease in dogs, with a growing incidence related to the
age of the animal. Nanotechnology is being employed in the veterinary field in the same …

Nanobiotechnological approaches in osteosarcoma therapy: versatile (nano) platforms for theranostic applications

Y Jiang, K He - Environmental Research, 2023 - Elsevier
Constructive achievements in the field of nanobiotechnology and their translation into
clinical course have led to increasing attention towards evaluation of their use for treatment …

Exosomes in bone cancer: unveiling their vital role in diagnosis, prognosis, and therapeutic advancements

S Ghosh, AA Mahajan, A Dey, RL Rajendran… - Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Bone cancer among adolescents and children exhibits varying survival outcomes based on
disease state. While localized bone cancer cases have a survival rate exceeding 70 …

Doxorubicin-loaded lipid nanoparticles coated with calcium phosphate as a potential tool in human and canine osteosarcoma therapy

D Chirio, S Sapino, G Chindamo, E Peira, C Vercelli… - Pharmaceutics, 2022 - mdpi.com
Osteosarcoma (OSA) is the most frequently diagnosed primary malignant bone tumor in
humans and dogs. In both species, standard chemotherapy can be limited by multidrug …

Nanocarriers in Veterinary Medicine: A Challenge for Improving Osteosarcoma Conventional Treatments

S Sapino, G Chindamo, D Chirio, S Morel, E Peira… - Nanomaterials, 2022 - mdpi.com
In recent years, several nanocarrier-based drug delivery systems, such as polymeric
nanoparticles, solid lipid nanoparticles, metallic nanoparticles, liposomes, and others, have …

Co-Treatment of Caco-2 Cells with Doxorubicin and Gold Nanoparticles Produced from Cyclopia intermedia Extracts or Mangiferin Enhances Drug Effects

JA Aboyewa, NRS Sibuyi, M Goboza, LA Murtz… - Nanomaterials, 2022 - mdpi.com
Mangiferin (MGF) is a natural and valuable polyphenol found in significant levels in many
plant species, including Cyclopia intermedia (C. intermedia). In a previous study, we …

[HTML][HTML] Human and canine osteosarcoma cell lines: How do they react upon incubation with calcium phosphate-coated lipid nanoparticles carrying doxorubicin and …

S Sapino, E Peira, D Chirio, G Chindamo… - International Journal of …, 2025 - Elsevier
Osteosarcoma (OSA) is a bone cancer that affects both humans and animals, with dogs
being particularly vulnerable. Standard therapy is often limited by multidrug resistance …