Respiratory disorders, especially non-communicable, chronic inflammatory diseases, are
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …

Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

Alzheimer's disease (AD) is the most common type of dementia, and promptly diagnosis of
AD is crucial for delaying the development of disease and improving patient quality of life …

Pathogenic bacteria cause various infections worldwide, especially in immunocompromised
and other susceptible individuals, and are also associated with high infant mortality rates in …

MicroRNA (miRNA or miR) therapeutics in cancer are based on targeting or mimicking
miRNAs involved in cancer onset, progression, angiogenesis, epithelial-mesenchymal …

Today obesity and type 2 diabetes (T2D) have both reached epidemic proportions.
However, our current understanding of the primary mechanisms leading to these diseases is …

Interleukin-8 (IL-8) is a neutrophil chemokine that is encoded on the CXCL8 gene. Normally
CXCL8 expression is repressed due to histone deacetylation, octamer-1 binding to the …

Macrophages play a central role in innate immunity as the first line of defense against
pathogen infection. Upon exposure to inflammatory stimuli, macrophages rapidly respond …

Overweight and obesity are major problems in today's society, driving the prevalence of
diabetes and its related complications. It is important to understand the molecular …

Chronic lung disease has become a leading cause of death in recent years. Despite several
attempts to discover and develop new therapeutic approaches, patients often suffer a poor …