The compilation of ligand and structure-based molecular modeling methods has become an important practice in virtual screening applied to drug discovery. This systematic review …
Diabetes mellitus type 2 (T2DM) can be managed by targeting dipeptidyl peptidase-4 (DPP- 4), an enzyme that breaks down and deactivates peptides such as GIP and GLP-1. In this …
Herein, we explored an environmentally benign synthesis of pyrazolo [5, 1-b] quinazoline-3- carboxylate derivatives 4 (au) as potential antimicrobial, antitubercular as well as …
A new series of thiadiazole derivatives (3a-3j) were designed and synthesized. Their structures were confirmed by spectral data and then subjected to in vitro assessment …