Recent progresses in chalcone derivatives as potential anticancer agents
J Yang, J Lv, S Cheng, T Jing, T Meng… - Anti-Cancer Agents …, 2023 - ingentaconnect.com
Chalcones are members of the flavonoid family and act as intermediates in the biosynthesis
of flavonoids, which are widespread in plants. Meanwhile, chalcones are important …
of flavonoids, which are widespread in plants. Meanwhile, chalcones are important …
QSAR, ADMET, molecular docking, and dynamics studies of 1, 2, 4-triazine-3 (2H)-one derivatives as tubulin inhibitors for breast cancer therapy
M Moussaoui, S Baammi, H Soufi, M Baassi… - Scientific Reports, 2024 - nature.com
Breast cancer remains a leading cause of cancer-related deaths among women globally,
necessitating the development of more effective therapeutic agents with minimal side effects …
necessitating the development of more effective therapeutic agents with minimal side effects …
Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors
Novel imidazole-chalcone derivatives were designed and synthesized as tubulin
polymerization inhibitors and anticancer agents. The antiproliferative activity of the imidazole …
polymerization inhibitors and anticancer agents. The antiproliferative activity of the imidazole …
Dual human carbonic anhydrase/cyclooxygenase-2 inhibitors: a promising approach for cancer treatment
M Mahboubi-Rabbani, A Zarghi - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
Human Carbonic Anhydrase (hCA) and Cyclooxygenase-2 (COX-2) have been known for a
long to be chiefly involved in both the pathogenesis and progression of cancer and cancer …
long to be chiefly involved in both the pathogenesis and progression of cancer and cancer …
3D‐QSAR‐Based Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Tubulin Inhibitors with Potential Anticancer Activity
In this study, we aimed to develop a pharmacophore‐based three‐dimensional quantitative
structure activity relationship (3D‐QSAR) for a set including sixty‐two cytotoxic quinolines (1 …
structure activity relationship (3D‐QSAR) for a set including sixty‐two cytotoxic quinolines (1 …
[HTML][HTML] Design, synthesis, and biological evaluation of novel 5, 6, 7-trimethoxy quinolines as potential anticancer agents and tubulin polymerization inhibitors
Materials and Methods: The cytotoxicity of the newly synthesized compounds was assessed
against different human cancer cell lines including MCF-7, A2780, MCF-7/MX, A2780/RCIS …
against different human cancer cell lines including MCF-7, A2780, MCF-7/MX, A2780/RCIS …
[HTML][HTML] Synthesis and biological evaluation of oxazinonaphthalene-3-one derivatives as potential anticancer agents and tubulin inhibitors
S Mirzaei, M Qayumov, F Gangi… - Iranian Journal of …, 2020 - ncbi.nlm.nih.gov
Materials and Methods: The cytotoxic activity of the synthesized compounds was evaluated
against four human cancer cell lines including A2780 (human ovarian carcinoma) …
against four human cancer cell lines including A2780 (human ovarian carcinoma) …
A Novel Magnetic Nanocomposite (Fe3O4@Saponin/Cr(III)) as a Potential Recyclable Catalyst for the Synthesis of β- Acetamidoketones Derivatives
M Kiani, H Anaraki-Ardakani… - Polycyclic Aromatic …, 2023 - Taylor & Francis
A natural based magnetic catalyst (nano-Fe3O4@ Saponin/Cr (III)) was synthesized using
CrCl3. 6H2O compounds on a nano-Fe3O4@ Saponin surface as a novel recyclable …
CrCl3. 6H2O compounds on a nano-Fe3O4@ Saponin surface as a novel recyclable …
[HTML][HTML] Synthesis and biological evaluation of novel quinoline analogs of ketoprofen as multidrug resistance protein 2 (MRP2) inhibitors
F Mosaffa, F Hadizadeh, F Fathi, ZE Nasab… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Objective (s): A new series of quinoline analogs of ketoprofen was designed and
synthesized as multidrug resistance protein 2 (MRP2) inhibitors using ketoprofen as the lead …
synthesized as multidrug resistance protein 2 (MRP2) inhibitors using ketoprofen as the lead …