The major human spirochetal pathogens (Leptospira, Borrelia, and Treponema) are difficult
to diagnose and lack vaccines to prevent infections. Infection by these spirochetes does not …

Defining the cellular factors that drive growth rate and proteome composition is essential for
understanding and manipulating cellular systems. In bacteria, ribosome concentration is …

Bacterial chromosomes are large molecules that need to be highly compacted to fit inside
the cells. Chromosome compaction must facilitate and maintain key biological processes …

As an enzootic pathogen, the Lyme disease bacterium Borrelia burgdorferi possesses
multiple copies of chemotaxis proteins, including two chemotaxis histidine kinases (CHK) …

Ornithodoros turicata is a vector of relapsing fever spirochetes in North America and
transmits Borrelia turicatae to a variety of vertebrate hosts. The remarkably long lifespan of …

Transposable elements (TEs) play a pivotal role in the evolution of genomes across all life
domains.'Miniature Inverted-repeat Transposable-Elements'(MITEs) are non-autonomous …

ABSTRACT The Lyme disease spirochete Borrelia burgdorferi cycles between immature
black-legged ticks (Ixodes scapularis) and vertebrate reservoir hosts, such as rodents …

The bacterium responsible for Lyme disease, Borrelia burgdorferi, accumulates high levels
of manganese without iron and possesses a polyploid genome, characteristics suggesting …

Transposable elements (TEs) have a pivotal role in the evolution of genomes across all life
domains.“Miniature Inverted-repeat Transposable-Elements”(MITEs) are non-autonomous …

Borrelia burgdorferi, a causative agent of Lyme disease, contains the most segmented
bacterial genome known to date, with one linear chromosome and over twenty plasmids …