The continued threat of emerging flaviviruses

TC Pierson, MS Diamond - Nature microbiology, 2020 - nature.com
Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …

Recent progress in Lyme disease and remaining challenges

JR Bobe, BL Jutras, EJ Horn, ME Embers… - Frontiers in …, 2021 - frontiersin.org
Lyme disease (also known as Lyme borreliosis) is the most common vector-borne disease in
the United States with an estimated 476,000 cases per year. While historically, the long-term …

Exploring the reservoir hosts of tick-borne encephalitis virus

A Michelitsch, K Wernike, C Klaus, G Dobler, M Beer - Viruses, 2019 - mdpi.com
Tick-borne encephalitis virus (TBEV) is an important arbovirus, which is found across large
parts of Eurasia and is considered to be a major health risk for humans. Like any other …

Tick-borne flaviviruses, with a focus on Powassan virus

G Kemenesi, K Bányai - Clinical microbiology reviews, 2018 - Am Soc Microbiol
The tick-borne pathogen Powassan virus is a rare cause of encephalitis in North America
and the Russian Far East. The number of documented cases described since the discovery …

Human pathogens associated with the blacklegged tick Ixodes scapularis: a systematic review

MP Nelder, CB Russell, NJ Sheehan, B Sander… - Parasites & vectors, 2016 - Springer
Abstract Background The blacklegged tick Ixodes scapularis transmits Borrelia burgdorferi
(sensu stricto) in eastern North America; however, the agent of Lyme disease is not the sole …

Emerging cases of Powassan virus encephalitis in New England: clinical presentation, imaging, and review of the literature

A Piantadosi, DB Rubin, DP McQuillen… - Clinical Infectious …, 2016 - academic.oup.com
Background. Powassan virus (POWV) is a rarely diagnosed cause of encephalitis in the
United States. In the Northeast, it is transmitted by Ixodes scapularis, the same vector that …

Phylogeographic reconstruction of the emergence and spread of Powassan virus in the northeastern United States

CBF Vogels, DE Brackney, AP Dupuis… - Proceedings of the …, 2023 - National Acad Sciences
Powassan virus is an emerging tick-borne virus of concern for public health, but very little is
known about its transmission patterns and ecology. Here, we expanded the genomic dataset …

Identification of Novel Viruses in Amblyomma americanum, Dermacentor variabilis, and Ixodes scapularis Ticks

R Tokarz, S Sameroff, T Tagliafierro, K Jain… - Msphere, 2018 - Am Soc Microbiol
Ticks carry a wide range of known human and animal pathogens and are postulated to carry
others with the potential to cause disease. Here we report a discovery effort wherein …

Ixodes scapularis Tick Saliva Proteins Sequentially Secreted Every 24 h during Blood Feeding

TK Kim, L Tirloni, AFM Pinto, J Moresco… - PLoS neglected …, 2016 - journals.plos.org
Ixodes scapularis is the most medically important tick species and transmits five of the 14
reportable human tick borne disease (TBD) agents in the USA. This study describes LC …

Incrimination of shrews as a reservoir for Powassan virus

HK Goethert, TN Mather, RW Johnson… - Communications …, 2021 - nature.com
Powassan virus lineage 2 (deer tick virus) is an emergent threat to American public health,
causing severe neurologic disease. Its life cycle in nature remains poorly understood. We …