Taking into account the complexity and limitations of clinical assessment in hypertrophic
cardiomyopathy (HCM), imaging techniques play an essential role in the evaluation of …

Amyloidoses represent a group of diseases characterized by the pathological accumulation
in the extracellular area of insoluble misfolded protein material called “amyloid”. The …

Abstract Lower Urinary Tract Symptoms (LUTS) are frequently present in the general
population as patients age with approximately a third of individuals experiencing LUTS …

REPORT order from most to least prevalent, are Val122Ile, Thr60Ala, and Val30Met. 13
Globally, the most common mutations, in order from most to least, are Val30Met, Val122Ile …

Transthyretin (TTR) amyloidosis (ATTR amyloidosis) is an underdiagnosed and important
type of cardiomyopathy and/or polyneuropathy that requires increased awareness within the …

Background: Familial amyloid polyneuropathy related to transthyretin gene (TTR-FAP) is a
life-threatening disease transmitted as an autosomal dominant trait. Val30Met mutation …

Cardiac amyloidosis is characterized by clinically significant extracellular amyloid infiltration
of the heart that is usually, but not always, associated with the involvement of other organs …

Background: Tafamidis, a non-NSAID highly specific transthyretin stabilizer, delayed
neurologic disease progression as measured by Neuropathy Impairment Score–Lower …

Objectives: We sought to evaluate noninvasive parameters by electrocardiography,
echocardiography, technetium-99m–3, 3-diphosphono-1, 2-propanodicarboxylic acid …

Background Amyloidosis is a group of diseases with the common pathophysiology of protein
misfolding and aberrant deposition in tissue. There are both acquired and hereditary forms …