The autoinflammatory diseases are characterized by seemingly unprovoked episodes of
inflammation, without high-titer autoantibodies or antigen-specific T cells. The concept was …

Graft-versus-host response after allogeneic hematopoietic stem cell transplantation (allo-
HCT) represents one of the most intense inflammatory responses observed in humans. Host …

Balanced chromosomal abnormalities (BCAs) represent a relatively untapped reservoir of
single-gene disruptions in neurodevelopmental disorders (NDDs). We sequenced BCAs in …

The last 10 years have witnessed the identification of a new class of intracellular pattern-
recognition molecules—the nucleotide-binding domain and leucine-rich repeat–containing …

The prognosis of head and neck squamous cell carcinoma (HNSCC) patients remains poor.
High-throughput sequencing data have laid a solid foundation for identifying genes related …

Extensive cell death with consecutive release of danger signals can cause immune-
mediated tissue destruction. The abundance of cell death is likely to determine the …

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only treatment with
curative potential for certain aggressive hematopoietic malignancies. Its success is limited …

Nucleotide‐binding oligomerization domain receptors (NOD‐like receptors, NLR s) are
intracellular proteins that are chiefly known for their critical functions in inflammatory …

Background Vaccination against severe acute respiratory syndrome coronavirus type 2 is
highly effective in preventing infection and reducing the severity of coronavirus disease …

Lower gastrointestinal (GI) tract graft-versus-host disease (GVHD) is the predominant cause
of morbidity and mortality from GVHD after allogeneic stem cell transplantation. Recent data …