Conserved chamber-specific polyploidy maintains heart function in Drosophila
A Chakraborty, NG Peterson, JS King… - …, 2023 - journals.biologists.com
Developmentally programmed polyploidy (whole-genome duplication) of cardiomyocytes is
common across evolution. Functions of such polyploidy are essentially unknown. Here, in …
common across evolution. Functions of such polyploidy are essentially unknown. Here, in …
In-depth phosphoproteomic profiling of the insulin signaling response in heart tissue and cardiomyocytes unveils canonical and specialized regulation
Background Insulin signaling regulates cardiac substrate utilization and is implicated in
physiological adaptations of the heart. Alterations in the signaling response within the heart …
physiological adaptations of the heart. Alterations in the signaling response within the heart …
Evaluation of a large-scale aptamer proteomics platform among patients with kidney failure on dialysis
Background Patients with kidney failure suffer high mortality, and we currently lack markers
for risk stratification for these patients. We carried out a quality control study of a modified …
for risk stratification for these patients. We carried out a quality control study of a modified …
Incident heart failure in chronic kidney disease: proteomics informs biology and risk stratification
Abstract Background and Aims Incident heart failure (HF) among individuals with chronic
kidney disease (CKD) incurs hospitalizations that burden patients and health care systems …
kidney disease (CKD) incurs hospitalizations that burden patients and health care systems …