Introduction Decreased libido in middle-aged and elderly men is often difficult to treat, and
identifying the risk factors affecting decreased libido is important for the clinical management …

Introduction The use of current available treatment for male erectile dysfunction (ED) has
some limitations that are related to efficacy and adverse effects. Nanotechnology has been …

The outbreak of the COVID-19 pandemic in China has become an urgent health and
economic challenge. The objective of the current work was to evaluate the efficacy of the …

To avoid the first-pass metabolism of avanafil (AVA) and its altered absorption in the
presence of food after oral administration, this study aimed to investigate the potential of …

Erectile dysfunction (ED), is a common and multidimensional sexual disorder, which
comprises changes among any of the processes of the erectile response such as organic …

Erectile dysfunction (ED) affects middle and older age and occurrence increasing with age
of men. PDE5 inhibitors are commonly used for the treatment of ED. The incidences of …

The highly effective phosphodiesterase type 5 inhibitor (avanafil; AVA) is routinely
prescribed to treat erectile dysfunction. The drug has poor oral bioavailability and undergoes …

The outbreak of the COVID-19 pandemic in China has become an urgent health and
economic challenge. The objective of the current work was to evaluate the efficacy of the …

Introduction: The use of current available treatment for male erectile dysfunction (ED) has
some limitations that are related to efficacy and adverse effects. Nanotechnology has been …

A buccal tablet formulation has a polyvinylpyrrolidone K-90 as a solid dispersion polymer, a
hydroxypropyl methylcellulose as a mucoadhesive polymer, a sodium deoxycholate as …