Probing organoid metabolism using fluorescence lifetime imaging microscopy (FLIM): The next frontier of drug discovery and disease understanding
Organoid models have been used to address important questions in developmental and
cancer biology, tissue repair, advanced modelling of disease and therapies, among other …
cancer biology, tissue repair, advanced modelling of disease and therapies, among other …
Spectroscopic techniques for monitoring stem cell and organoid proliferation in 3D environments for therapeutic development
Spectroscopic techniques for monitoring stem cell and organoid proliferation have gained
significant attention in therapeutic development. Spectroscopic techniques such as …
significant attention in therapeutic development. Spectroscopic techniques such as …
Organoid imaging: seeing development and function
R Keshara, YH Kim… - Annual review of cell and …, 2022 - annualreviews.org
Organoids are miniaturized and simplified versions of an organ produced in vitro from stem
or progenitor cells. They are used as a model system consisting of multiple cell types …
or progenitor cells. They are used as a model system consisting of multiple cell types …
Advanced 3D imaging and organoid bioprinting for biomedical research and therapeutic applications
Organoid cultures offer a valuable platform for studying organ-level biology, allowing for a
closer mimicry of human physiology compared to traditional two-dimensional cell culture …
closer mimicry of human physiology compared to traditional two-dimensional cell culture …
Retinal organoids from human-induced pluripotent stem cells: From studying retinal dystrophies to early diagnosis of Alzheimer's and Parkinson's disease
MI Móvio, TH de Lima-Vasconcellos… - Seminars in Cell & …, 2023 - Elsevier
Human-induced pluripotent stem cells (hiPSCs) have provided new methods to study
neurodegenerative diseases. In addition to their wide application in neuronal disorders …
neurodegenerative diseases. In addition to their wide application in neuronal disorders …
Revealing the clinical potential of high-resolution organoids
The symbiotic interplay of organoid technology and advanced imaging strategies yields
innovative breakthroughs in research and clinical applications. Organoids, intricate three …
innovative breakthroughs in research and clinical applications. Organoids, intricate three …
[HTML][HTML] The prospects for retinal organoids in treatment of retinal diseases
Retinal degeneration (RD) is a significant cause of incurable blindness worldwide.
Photoreceptors and retinal pigmented epithelium are irreversibly damaged in advanced RD …
Photoreceptors and retinal pigmented epithelium are irreversibly damaged in advanced RD …
Label-free optical imaging and sensing for quality control of stem cell manufacturing
Human stem cells provide emerging methods for drug screening, disease modeling, and
personalized patient therapies. To meet this growing demand for scale-up, stem cell …
personalized patient therapies. To meet this growing demand for scale-up, stem cell …
[HTML][HTML] Generation of human patient iPSC-derived retinal organoids to model retinitis pigmentosa
C Ma, K Jin, ZB Jin - JoVE (Journal of Visualized …, 2022 - www-jove-com-443.vpn.cdutcm.edu …
Retinitis pigmentosa (RP) is a rare and inherited retinal degenerative disease with a
prevalence of approximately 1/4,000 people worldwide. The majority of RP patients have …
prevalence of approximately 1/4,000 people worldwide. The majority of RP patients have …
[HTML][HTML] Label-free multimodal non-linear optical imaging of three-dimensional cell cultures
W Zhao, D Sun, S Yue - Frontiers in Physics, 2023 - frontiersin.org
3D cell cultures recapitulate tissue-specific diversity and better mimic the in vivo conditions
compared to 2D cell cultures. Although confocal fluorescence microscopy is probably the …
compared to 2D cell cultures. Although confocal fluorescence microscopy is probably the …