During aging, deterioration in cardiac structure and function leads to increased susceptibility
to heart failure. The need for interventions to combat this age-related cardiac decline is …

It is widely accepted that senescent cells accumulate with aging. They are characterized by
replicative arrest and the release of a myriad of factors commonly called the senescence …

Aging leads to increased cellular senescence and is associated with decreased potency of
tissue‐specific stem/progenitor cells. Here, we have done an extensive analysis of cardiac …

Adult stem cells are fundamental to maintain tissue homeostasis, growth, and regeneration.
They reside in specialized environments called niches. Following activating signals, they …

The significance of cardiac stem cell (CSC) populations for cardiac regeneration remains
disputed. Here, we apply the most direct definition of stem cell function (the ability to replace …

Cardiovascular regenerative therapies are pursued on both basic and translational levels.
Although efficacy and value of cell therapy for myocardial regeneration can be debated …

Cardiovascular diseases (CVD) are predominantly an aging disease. Important sex-specific
differences exist and the mechanism (s) by which this sex-by-age interaction influences CVD …

The purpose of this review is to assess the state-of-the-art fabrication methods, advances in
genome editing, and the use of machine learning to shape the prospective growth in cardiac …

Simple Summary Aging and frailty are complex processes implicating multifactorial
mechanisms, which demand for new therapeutic strategies against their devastating effects …

Adult stem/progenitor are a small population of cells that reside in tissue-specific niches and
possess the potential to differentiate in all cell types of the organ in which they operate. Adult …