European guideline on indications, performance and clinical impact of 13C‐breath tests in adult and pediatric patients: An EAGEN, ESNM, and ESPGHAN consensus …

J Keller, HF Hammer, PR Afolabi, M Benninga… - UEG …, 2021 - Wiley Online Library
Introduction 13C‐breath tests are valuable, noninvasive diagnostic tests that can be widely
applied for the assessment of gastroenterological symptoms and diseases. Currently, the …

13C-Breath testing in animals: theory, applications, and future directions

MD McCue, KC Welch - Journal of Comparative Physiology B, 2016 - Springer
The carbon isotope values in the exhaled breath of an animal mirror the carbon isotope
values of the metabolic fuels being oxidized. The measurement of stable carbon isotopes in …

The carbon isotope ratio of breath is elevated by short-term and long-term added sugar and animal protein intake in a controlled feeding study

DM O'Brien, LS Freedman, P Rivera… - The American Journal of …, 2024 - Elsevier
Background The breath carbon isotope ratio (CIR) was recently identified as a noninvasive
candidate biomarker of short-term added sugars (AS) intake. Objectives This study aimed to …

CH4/CO2 Ratios and Carbon Isotope Enrichment Between Diet and Breath in Herbivorous Mammals

TE Cerling, SM Bernasconi, LS Hofstetter… - Frontiers in Ecology …, 2021 - frontiersin.org
Breath and diet samples were collected from 29 taxa of animals at the Zurich and Basel
Zoos to characterize the carbon isotope enrichment between breath and diet. Diet samples …

Learning to starve: impacts of food limitation beyond the stress period

MD McCue, JS Terblanche… - Journal of Experimental …, 2017 - journals.biologists.com
Starvation is common among wild animal populations, and many individuals experience
repeated bouts of starvation over the course of their lives. Although much information has …

Water restriction increases oxidation of endogenous amino acids in house sparrows (Passer domesticus)

EJ Rogers, AR Gerson - Journal of Experimental Biology, 2024 - journals.biologists.com
Animals can cope with dehydration in a myriad of ways, both behaviorally and
physiologically. The oxidation of protein produces more metabolic water per kilojoule than …

Carbon stable‐isotope tracking in breath for comparative studies of fuel use

KC Welch Jr, F Péronnet, KA Hatch… - Annals of the New …, 2016 - Wiley Online Library
Almost half a century ago, researchers demonstrated that the ratio of stable carbon isotopes
in exhaled breath of rats and humans could reveal the oxidation of labeled substrates in …

Exogenous stress hormones alter energetic and nutrient costs of development and metamorphosis

LJ Kirschman, MD McCue, JG Boyles… - Journal of …, 2017 - journals.biologists.com
Variation in environmental conditions during larval life stages can shape development
during critical windows and have lasting effects on the adult organism. Changes in larval …

Digesting pythons quickly oxidize the proteins in their meals and save the lipids for later

MD McCue, RM Guzman… - The Journal of …, 2015 - journals.biologists.com
Pythons digesting rodent meals exhibit up to 10-fold increases in their resting metabolic rate
(RMR); this increase in RMR is termed specific dynamic action (SDA). Studies have shown …

Dehydration causes increased reliance on protein oxidation in mice: a test of the protein-for-water hypothesis in a mammal

MD McCue, J Sandoval, J Beltran… - Physiological and …, 2017 - journals.uchicago.edu
During fasting, animals rely on a mixture of fats, carbohydrates, and proteins that are derived
solely from endogenous sources. The relative contributions of these metabolic fuels chiefly …