Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment

R Liu, C Luo, Z Pang, J Zhang, S Ruan, M Wu… - Chinese chemical …, 2023 - Elsevier
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …

Recent progress of MOF-functionalized nanocomposites: from structure to properties

K Xu, S Zhang, X Zhuang, G Zhang, Y Tang… - Advances in Colloid and …, 2024 - Elsevier
Metal-organic frameworks (MOFs) are novel crystalline porous materials assembled from
metal ions and organic ligands. The adaptability of their design and the fine-tuning of the …

[HTML][HTML] Engineering nanoparticle toolkits for mRNA delivery

B Sun, W Wu, EA Narasipura, Y Ma, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
The concept of using mRNA to produce its own medicine in situ in the body makes it an ideal
drug candidate, holding great potential to revolutionize the way we approach medicine. The …

Targeting acidogenic metabolism by engineering self-catalytic siRNA nanocarriers/nanocatalysts for amplified tumor apoptosis/ferroptosis

L Zhou, W Feng, L Chen, H Huang, S Huang, Q Chen… - Nano Today, 2022 - Elsevier
Nanocatalytic medicine holds great potential in inhibiting tumor progression based on the
synergistic catalytic production of toxic reactive oxygen species (ROS) between fenton …

Cellular Trafficking of Nanotechnology‐Mediated mRNA Delivery

P Huang, H Deng, C Wang, Y Zhou… - Advanced …, 2024 - Wiley Online Library
Messenger RNA (mRNA)‐based therapy has emerged as a powerful, safe, and rapidly
scalable therapeutic approach that involves technologies for both mRNA itself and the …

Advancements and challenges in mRNA and ribonucleoprotein-based therapies: From delivery systems to clinical applications

Z Eftekhari, H Zohrabi, A Oghalaie, T Ebrahimi… - … Therapy-Nucleic Acids, 2024 - cell.com
The use of mRNA and ribonucleoproteins (RNPs) as therapeutic agents is a promising
strategy for treating diseases like cancer and infectious diseases. This review provides …

Dual-targeted metal ion network hydrogel scaffold for promoting the integrated repair of Tendon–bone interfaces

J Ma, H Yu, X Zhang, Z Xu, H Hu, J Liu… - … Applied Materials & …, 2024 - ACS Publications
The tendon–bone interface has a complex gradient structure vital for stress transmission and
pressure buffering during movement. However, injury to the gradient tissue, especially the …

Nrf2 silencing amplifies DNA photooxidative damage to activate the STING pathway for synergistic tumor immunotherapy

S Sun, M Yu, L Yu, W Huang, M Zhu, Y Fu, L Yan… - Biomaterials, 2023 - Elsevier
Photodynamic therapy (PDT)-mediated antitumor immune response depends on oxidative
stress intensity and subsequent immunogenic cell death (ICD) in tumor cells, yet the …

Synergistic Nanoarchitectonics: Precision Membrane Engineering for Rare Earth Selective Separation

Z Lv, X Zhang, Q Gao, C Wen, Y He… - Advanced Functional …, 2024 - Wiley Online Library
Rare earth elements (REEs) are vital in high‐tech industries and defense due to their
strategic significance. Crafting an efficient membranes channel for REE separation poses a …

Reprogramming mitochondrial metabolism of macrophages by miRNA-released microporous coatings to prevent peri-implantitis

H Zhang, Y Yuan, H Xue, R Yu, X Jin, X Wu… - Journal of …, 2023 - Springer
Although various new biomaterials have enriched the methods for peri-implant inflammation
treatment, their efficacy is still debated, and secondary operations on the implant area have …