Psoriasis and the metabolic syndrome

P Gisondi, AC Fostini, I Fossà, G Girolomoni… - Clinics in …, 2018 - Elsevier
Chronic plaque psoriasis is an immune-mediated inflammatory skin disease that is strongly
associated with the clinical features of the metabolic syndrome (MetS), including abdominal …

Psoriasis as a systemic disease

I Grozdev, N Korman, N Tsankov - Clinics in dermatology, 2014 - Elsevier
Psoriasis is an inflammatory immune-mediated disease that affects the skin and has
pathogenic effects with systemic impact. The relationship between psoriasis and …

Crosstalk between cholesterol metabolism and psoriatic inflammation

L Luo, Y Guo, L Chen, J Zhu, C Li - Frontiers in Immunology, 2023 - frontiersin.org
Psoriasis is a chronic autoinflammatory skin disease associated with multiple comorbidities,
with a prevalence ranging from 2 to 3% in the general population. Decades of preclinical …

The association between psoriasis and dyslipidaemia: a systematic review

C Ma, CT Harskamp, EJ Armstrong… - British Journal of …, 2013 - academic.oup.com
Psoriasis may be associated with dyslipidaemia, a known risk factor for cardiovascular
disease. This systematic review aims to synthesize evidence for the association between …

Drugs that ameliorate epicardial adipose tissue inflammation may have discordant effects in heart failure with a preserved ejection fraction as compared with a …

M Packer - Journal of Cardiac Failure, 2019 - Elsevier
Heart failure with a preserved ejection fraction (HFpEF) and heart failure with a reduced
ejection fraction (HFrEF) have distinctive pathophysiologies, and thus, therapeutic …

Statins and autoimmunity: State-of-the-art

S Dehnavi, N Sohrabi, M Sadeghi, P Lansberg… - Pharmacology & …, 2020 - Elsevier
HMG-CoA reductase inhibitors, or statins, are potent plasma LDL-cholesterol (LDL-c)
lowering agents. Since the introduction of the first statin, lovastatin, in 1987, accumulating …

Update on obesity in psoriasis patients

D Vata, BM Tarcau, IA Popescu, IA Halip, AI Patrascu… - Life, 2023 - mdpi.com
Psoriasis is a chronic inflammatory skin condition, with genetic, epigenetic, environmental,
and lifestyle factors contributing to its onset and recurrence. Severe psoriasis has a great …

Effects of Hypolipidemic drugs on psoriasis

M Matwiejuk, H Mysliwiec, O Jakubowicz-Zalewska… - Metabolites, 2023 - mdpi.com
Psoriasis is a chronic, systematic, inflammatory disease in which multiple metabolic and
immunologic disturbances lead to lipid abnormalities, impaired glucose tolerance, metabolic …

[PDF][PDF] The effect of statins on psoriasis severity: a meta-analysis of randomized clinical trials

M Socha, A Pietrzak, E Grywalska, D Pietrzak… - Archives of Medical …, 2019 - termedia.pl
Results Of 279 records identified, there were 5 eligible RCTs, with a total of 223 patients,
including 128 patients who received a statin (atorvastatin or simvastatin). The improvement …

Combination treatments for psoriasis: a systematic review and meta-analysis

EE Bailey, EH Ference, A Alikhan… - Archives of …, 2012 - jamanetwork.com
Objective To summarize the current state of evidence for combination topical and systemic
therapies for mild to severe psoriasis. Data Sources We performed a systematic search for …