Quinoline anticancer agents active on DNA and DNA-interacting proteins: From classical to emerging therapeutic targets

A Lauria, G La Monica, A Bono, A Martorana - European Journal of …, 2021 - Elsevier
Quinoline is one of the most important and versatile nitrogen heterocycles embodied in
several biologically active molecules. Within the numerous quinolines developed as …

A patent review of topoisomerase I inhibitors (2016–present)

A Selas, E Martin-Encinas, M Fuertes… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Topoisomerases are important targets for therapeutic improvement in the
treatment of some diseases, including cancer. Inhibitors and poisons of topoisomerase I can …