Capillary electrophoresis-SELEX (CE-SELEX) was used to select ssDNA aptamers with
affinity for HIV reverse transcriptase (HIVRT). A library of ssDNA was incubated with HIVRT …

This contribution reviews the synthesis of a range of experimental drugs designed for and
aiming at antiviral chemotherapy of severe acute respiratory syndrome (SARS) coronavirus …

This article reviews the current status of classes of HIV-1 integrase enzyme inhibitors. These
classes include peptide-based inhibitors, natural products, polyhydroxylated aromatics …

A novel organic cocrystal salt hydrate (CTPTH) of Chromotropic acid with 1, 10-
phenanthroline was successfully obtained using both traditional solution method and liquid …

A series of compounds bearing a Tetrazole and Triazine ring motif conjugated with a
SO2NH function were synthesized and investigated for their antiamoebic potency …

The tetramer of ethylenesulfonic acid (U-9843) is a potent inhibitor of HIV-1 RT* and
possesses excellent antiviral activity at nontoxic doses in HIV-1 infected lymphocytes grown …

Conclusion Sulfonate groups can be used as hydrogen bond donors and acceptors in
drugs, improving their interactions with biological targets, thereby enhancing the affinity and …

A new series of N‐(pyrimidin‐2‐yl) benzenesulfonamide derivatives, 3a–3i and 4a–4i, was
synthesized from pyrimidin‐2‐amines, 2a–2i, with the aim to explore their effects on in vitro …

Zinc metalloproteinases meprin α and meprin β are implicated in a variety of diseases, such
as fibrosis, inflammation and neurodegeneration, however, there are no selective small …

The human immunodeficiency virus (HIV) epidemic is an important medical problem.
Although combination drug regimens have produced dramatic decreases in viral load …