Osteosarcoma

HC Beird, SS Bielack, AM Flanagan, J Gill… - Nature reviews Disease …, 2022 - nature.com
Osteosarcoma is the most common primary malignant tumour of the bone. Osteosarcoma
incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in …

Naringenin: A potential flavonoid phytochemical for cancer therapy

M Motallebi, M Bhia, HF Rajani, I Bhia, H Tabarraei… - Life Sciences, 2022 - Elsevier
Naringenin is an important phytochemical which belongs to the flavanone group of
polyphenols, and is found mainly in citrus fruits like grapefruits and others such as tomatoes …

Ewing sarcoma—diagnosis, treatment, clinical challenges and future perspectives

SK Zöllner, JF Amatruda, S Bauer, S Collaud… - Journal of clinical …, 2021 - mdpi.com
Ewing sarcoma, a highly aggressive bone and soft-tissue cancer, is considered a prime
example of the paradigms of a translocation-positive sarcoma: a genetically rather simple …

Future directions in the treatment of osteosarcoma

A Smrke, PM Anderson, A Gulia, S Gennatas… - Cells, 2021 - mdpi.com
Osteosarcoma is the most common primary bone sarcoma and is often diagnosed in the 2nd–
3rd decades of life. Response to the aggressive and highly toxic neoadjuvant methotrexate …

[HTML][HTML] Stem cell membrane-coated abiotic nanomaterials for biomedical applications

I Ferreira-Faria, S Yousefiasl, A Macário-Soares… - Journal of controlled …, 2022 - Elsevier
Nanoscale materials have been extensively employed for diagnostic and therapeutic
purposes. However, the developed nanosystems still suffer from some limitations, namely …

Advances in osteosarcoma

I Panez-Toro, J Muñoz-García… - Current osteoporosis …, 2023 - Springer
Abstract Purpose of Review This article gives a brief overview of the most recent
developments in osteosarcoma treatment, including targeting of signaling pathways …

Small round cell sarcomas

F Cidre-Aranaz, S Watson, JF Amatruda… - Nature Reviews …, 2022 - nature.com
Undifferentiated small round cell sarcomas (SRCSs) of bone and soft tissue comprise a
heterogeneous group of highly aggressive tumours associated with a poor prognosis …

Drug resistance in osteosarcoma: emerging biomarkers, therapeutic targets and treatment strategies

CM Hattinger, MP Patrizio, L Fantoni, C Casotti… - Cancers, 2021 - mdpi.com
Simple Summary Despite the adoption of aggressive, multimodal treatment schedules, the
cure rate of high-grade osteosarcoma (HGOS) has not significantly improved in the last 30 …

Bacteria as a treasure house of secondary metabolites with anticancer potential

CD Mohan, S Rangappa, SC Nayak… - Seminars in cancer …, 2022 - Elsevier
Cancer stands in the frontline among leading killers worldwide and the annual mortality rate
is expected to reach 16.4 million by 2040. Humans suffer from about 200 different types of …

Rhabdomyosarcoma: current therapy, challenges, and future approaches to treatment strategies

A Zarrabi, D Perrin, M Kavoosi, M Sommer, S Sezen… - Cancers, 2023 - mdpi.com
Simple Summary Rhabdomyosarcoma (RMS) is a rare pediatric sarcoma affecting skeletal
muscle in children and young adults. It is responsible for 3% of all childhood malignant …