As a clinically approved treatment strategy, chemotherapy-mediated tumor suppression has
been compromised, and in spite of introducing various kinds of anticancer drugs, cancer …

Colorectal Cancer (CRC) is one of the most common gastrointestinal malignancies which
has quite a high mortality rate. Despite the advances made in CRC treatment, effective …

Background Oxaliplatin resistance is a complex process and has been one of the most
disadvantageous factors and indeed a confrontation in the procedure of colorectal cancer …

Oxaliplatin, as a first-line drug, frequently causes chemo-resistance in colorectal cancer
(CRC). The role of N6-methyladenosine (m6A) modification in multiple biological functions …

The hypoxic microenvironment contributes to the chemoresistance of many malignant
tumors including colorectal cancer (CRC). Accumulating studies have indicated that long …

Cancer has emerged as the most common cause of death in China. The change in lipid
metabolism has been confirmed to have a role in several tumor types, such as esophageal …

Background Because adverse reactions or drug resistance are often found after current
chemotherapies for metastatic colorectal cancer (mCRC), new treatments are still in …

Malignant tumors are always a critical threat to human health, with complex pathogenesis,
numerous causative factors, and poor prognosis. The features of cancers, such as gene …

Background Colorectal cancer (CRC) is the third most common cancer worldwide. Many
recent studies have demonstrated that different long non-coding RNAs (lncRNAs) are …

Oxaliplatin (OXA) is the first-line chemotherapy drug for metastatic colorectal cancer
(mCRC), and the emergence of drug resistance is a major clinical challenge. Although there …