Mesenchymal stem cells for regenerative medicine

Y Han, X Li, Y Zhang, Y Han, F Chang, J Ding - Cells, 2019 - mdpi.com
In recent decades, the biomedical applications of mesenchymal stem cells (MSCs) have
attracted increasing attention. MSCs are easily extracted from the bone marrow, fat, and …

Bioprinting of tissue engineering scaffolds

P Rider, ŽP Kačarević, S Alkildani… - Journal of tissue …, 2018 - journals.sagepub.com
Bioprinting is the process of creating three-dimensional structures consisting of biomaterials,
cells, and biomolecules. The current additive manufacturing techniques, inkjet-, extrusion …

[HTML][HTML] Human stem cell based corneal tissue mimicking structures using laser-assisted 3D bioprinting and functional bioinks

A Sorkio, L Koch, L Koivusalo, A Deiwick, S Miettinen… - Biomaterials, 2018 - Elsevier
There is a high demand for developing methods to produce more native-like 3D corneal
structures. In the present study, we produced 3D cornea-mimicking tissues using human …

Cultivated autologous limbal epithelial cell (CALEC) transplantation: Development of manufacturing process and clinical evaluation of feasibility and safety

UV Jurkunas, J Yin, LK Johns, S Li, H Negre… - Science …, 2023 - science.org
To treat unilateral limbal stem cell (LSC) deficiency, we developed cultivated autologous
limbal epithelial cells (CALEC) using an innovative xenobiotic-free, serum-free, antibiotic …

Corneal repair and regeneration: current concepts and future directions

M Mobaraki, R Abbasi, S Omidian Vandchali… - … in Bioengineering and …, 2019 - frontiersin.org
The cornea is a unique tissue and the most powerful focusing element of the eye, known as
a window to the eye. Infectious or non-infectious diseases might cause severe visual …

Wound-healing studies in cornea and skin: parallels, differences and opportunities

A Bukowiecki, D Hos, C Cursiefen… - International journal of …, 2017 - mdpi.com
The cornea and the skin are both organs that provide the outer barrier of the body. Both
tissues have developed intrinsic mechanisms that protect the organism from a wide range of …

Human limbal epithelial stem cell regulation, bioengineering and function

C Bonnet, S González, JAS Roberts… - Progress in retinal and …, 2021 - Elsevier
The corneal epithelium is continuously renewed by limbal stem/progenitor cells (LSCs), a
cell population harbored in a highly regulated niche located at the limbus. Dysfunction …

Therapeutic contact lens for scavenging excessive reactive oxygen species on the ocular surface

SW Choi, BG Cha, J Kim - ACS nano, 2020 - ACS Publications
Excessive reactive oxygen species (ROS) play a significant role in the pathogenesis of many
eye diseases. Controlling oxidative stress by reducing the amount of ROS is a potential …

Current trends and future perspective of mesenchymal stem cells and exosomes in corneal diseases

H Mansoor, HS Ong, AK Riau, TP Stanzel… - International journal of …, 2019 - mdpi.com
The corneal functions (transparency, refractivity and mechanical strength) deteriorate in
many corneal diseases but can be restored after corneal transplantation (penetrating and …

Vernal keratoconjunctivitis

D Singhal, P Sahay, PK Maharana, N Raj… - Survey of …, 2019 - Elsevier
Vernal keratoconjunctivitis, a chronic bilateral seasonal allergic inflammatory disease of the
eye, is an important cause of visual debilitation and impairment of quality of life in children …