Mortality in patients with pituitary disease

M Sherlock, J Ayuk, JW Tomlinson… - Endocrine …, 2010 - academic.oup.com
Pituitary disease is associated with increased mortality predominantly due to vascular
disease. Control of cortisol secretion and GH hypersecretion (and cardiovascular risk factor …

Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society Clinical Practice Guideline

ME Molitch, DR Clemmons… - The Journal of …, 2006 - academic.oup.com
Objective: The objective is to provide guidelines for the evaluation and treatment of adults
with GH deficiency (GHD). Participants: The chair of the Task Force was selected by the …

Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society clinical practice guideline

ME Molitch, DR Clemmons… - The Journal of …, 2011 - academic.oup.com
Objective: The aim was to update The Endocrine Society Clinical Practice Guideline on
Evaluation and Treatment of Adult Growth Hormone Deficiency (GHD) previously published …

The GH–IGF‐I axis and the cardiovascular system: clinical implications

A Colao - Clinical endocrinology, 2008 - Wiley Online Library
Summary Background GH and IGF‐I affect cardiac structure and performance. In the general
population, low IGF‐I has been associated with higher prevalence of ischaemic heart …

The growth hormone/insulin-like growth factor-I axis in exercise and sport

J Gibney, ML Healy, PH Sönksen - Endocrine reviews, 2007 - academic.oup.com
The syndrome of adult GH deficiency and the effects of GH replacement therapy provide a
useful model with which to study the effects of the GH/IGF-I axis on exercise physiology …

Cardiac effects of growth hormone in adults with growth hormone deficiency: a meta-analysis

P Maison, P Chanson - Circulation, 2003 - Am Heart Assoc
Background—Growth hormone (GH) treatment may improve morphological and functional
cardiac parameters in adults with GH deficiency (GHD). However, clinical trials reported to …

Determinants of cardiovascular risk in 2589 hypopituitary GH-deficient adults–a KIMS database analysis

R Abs, U Feldt-Rasmussen, AF Mattsson… - European Journal of …, 2006 - academic.oup.com
Objective The aim of the present study was to clarify the relationship between GH deficiency
(GHD) and some cardiovascular risk factors and to analyse the effect of GH replacement …

The cardiovascular system in growth hormone excess and growth hormone deficiency

G Lombardi, C Di Somma, LFS Grasso… - Journal of …, 2012 - Springer
The clinical conditions associated with GH excess and GH deficiency (GHD) are known to
be associated with an increased risk for the cardiovascular morbidity and mortality …

Growth hormone (GH) dose-response in young adults with childhood-onset GH deficiency: a two-year, multicenter, multiple-dose, placebo-controlled study

LE Underwood, KM Attie, J Baptista… - The Journal of …, 2003 - academic.oup.com
GH replacement therapy has been shown to improve abnormalities in body composition,
bone mineral density (BMD), lipid profile, and other changes resulting from GH deficiency …

Growth hormone treatment during hemodialysis in a randomized trial improves nutrition, quality of life, and cardiovascular risk

B Feldt-Rasmussen, M Lange, W Sulowicz… - Journal of the …, 2007 - journals.lww.com
Nutritional markers, such as lean body mass (LBM) and serum albumin, predict outcome in
dialysis patients, in whom protein-energy malnutrition is associated with increased morbidity …