[HTML][HTML] In vivo corneal elastography: A topical review of challenges and opportunities

G Lan, MD Twa, C Song, JP Feng, Y Huang… - Computational and …, 2023 - Elsevier
Clinical measurement of corneal biomechanics can aid in the early diagnosis, progression
tracking, and treatment evaluation of ocular diseases. Over the past two decades …

Molecular basis for mechanical properties of ECMs: proposed role of fibrillar collagen and proteoglycans in tissue biomechanics

FH Silver, N Kelkar, T Deshmukh - Biomolecules, 2021 - mdpi.com
Collagen and proteoglycans work in unison in the ECM to bear loads, store elastic energy
and then dissipate excess energy to avoid tissue fatigue and premature mechanical failure …

New forays into measurement of ocular biomechanics

E Hammelef, CJ Rapuano, DA Benedetto… - Current opinion in …, 2024 - journals.lww.com
Alterations in corneal biomechanics are known to occur in several corneal degenerative
diseases and after refractive surgical procedures. The measurement of corneal …

[HTML][HTML] In vivo determination of the human corneal elastic modulus using vibrational optical coherence tomography

MA Crespo, HJ Jimenez, T Deshmukh… - … Vision Science & …, 2022 - iovs.arvojournals.org
Purpose: To determine the in vivo elastic modulus of the human cornea using vibrational
optical coherence tomography (VOCT). Methods: Vibrational analysis coupled with optical …

Identification of Cancerous Skin Lesions Using Vibrational Optical Coherence Tomography (VOCT): Use of VOCT in Conjunction with Machine Learning to Diagnose …

FH Silver, A Mesica, M Gonzalez-Mercedes… - Cancers, 2022 - mdpi.com
Simple Summary Skin cancer detection is an important problem since it is the most common
form of cancer in the US and the number of cases is increasing in the US and worldwide …

The “Virtual Biopsy” of Cancerous Lesions in 3D: Non-Invasive Differentiation between Melanoma and Other Lesions Using Vibrational Optical Coherence …

FH Silver, T Deshmukh, N Kelkar, K Ritter, N Ryan… - …, 2021 - mdpi.com
Early detection of skin cancer is of critical importance to provide five year survival rates that
approach 99%. By 2050, one out of five Americans by age 70 will develop some form of skin …

Characterization of the biomechanical properties of skin using vibrational optical coherence tomography: Do changes in the biomechanical properties of skin stroma …

FH Silver, N Kelkar, T Deshmukh, K Ritter, N Ryan… - Biomolecules, 2021 - mdpi.com
Early detection of skin cancer is of critical importance since the five-year survival rate for
early detected skin malignancies is 99% but drops to 27% for cancer that has spread to …

A rapid method to noninvasively measure the viscoelastic properties of synthetic polymers using mechanical vibrations and photonics

FH Silver, M Gonzalez-Mercedes, A Mesica - Photonics, 2022 - mdpi.com
Noninvasive measurement of the viscoelastic properties of both natural and synthetic
polymers is important for the analysis of implant design and performance as well as in …

Dual-channel air-pulse optical coherence elastography for frequency-response analysis

C Song, W He, J Feng, MD Twa, Y Huang… - Biomedical Optics …, 2024 - opg.optica.org
Microliter air-pulse optical coherence elastography (OCE) has recently been proposed for
the characterization of soft-tissue biomechanics using transient, sub-nanometer to …

[HTML][HTML] Measurement of the Elastic Modulus of Cornea, Sclera and Limbus: The Importance of the Corneal-Limbus-Scleral Biomechanical Unit

FH Silver, T Deshmukh, D Benedetto… - Frontiers in Bioscience …, 2022 - imrpress.com
Background: Energy storage, transmission and dissipation are important considerations of
normal mechanical homeostasis. In this paper we present a new technique termed …