The malaria parasite is a unicellular eukaryotic organism which, during the course of its
complex life cycle, invades the red blood cells of its vertebrate host. As it grows and …

Apicomplexan parasites have complex life cycles, frequently split between different hosts
and reliant on rapid responses as the parasites react to changing environmental conditions …

* Departamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, São
Paulo 05508-90, Brasil† Dipartimento di Scienze Biomediche Sperimentali, Centro CNR …

Malaria parasites, Plasmodia, spend most of their asexual life cycle within red blood cells,
where they proliferate and mature. The erythrocyte cytoplasm has very low [Ca2+](< 100 …

Ca2+ is a ubiquitous intracellular messenger in malaria parasites with important functions in
asexual blood stages responsible for malaria symptoms, the preceding liver‐stage infection …

The methods developed by us in 1976 for the continuous culture of the erythrocytic stages of
Plasmodium falciparum make this organism available to a large variety of scientists. As a …

Intraerythrocyte growth of the malaria parasite Plasmodium falciparum induces a Ca2+-
permeable unselective cation conductance in the host cell membrane which is inhibited by …

The host hormone melatonin increases cytoplasmic Ca2+ concentration and synchronizes
Plasmodium cell cycle (Hotta, CT, ML Gazarini, FH Beraldo, FP Varotti, C. Lopes, RP …

The demand for novel, fast‐acting, and effective antimalarial medications is increasing
exponentially. Multidrug resistant forms of malarial parasites, which are rapidly spreading …

Molecular mechanisms by which signaling pathways operate in the malaria parasite and
control its development are promiscuous. Recently, we reported the identification of a …