The field of photopharmacology uses molecular photoswitches to establish control over the
action of bioactive molecules. It aims to reduce systemic drug toxicity and the emergence of …

Mass spectrometry imaging (MSI) is a powerful analytical technique that enables label-free
spatial localization and identification of molecules in complex samples. 1− 4 MSI …

Desorption electrospray ionization mass spectrometry imaging (DESI‐MSI) is one of the
least specimen destructive ambient ionization mass spectrometry tissue imaging methods. It …

Exploring the three-dimensional (3D) drug distribution within a single cell at nanoscale
resolution with mass spectrometry imaging (MSI) techniques is crucial in cellular biology, yet …

Mass spectrometry imaging (MSI) techniques make possible the spatial chemical
identification of analytes, especially for biological samples. As a universal energy source …

Since the introduction of desorption electrospray ionization (DESI) mass spectrometry (MS),
ambient MS methods have seen increased use in a variety of fields from health to food …

Highlights•Ambient ionization mass spectrometry provides chemical information from small
metabolites to polypeptides directly on biological samples.•Ambient ionization coupled …

The emerging ambient mass spectrometry imaging (MSI) enables to acquire molecular
images and information directly on the sample surface under the atmospheric environment …

Abstract Das Feld der Photopharmakologie nutzt durch Licht schaltbare Moleküle, um
Kontrolle über die Wirkung biologisch aktiver Verbindungen zu erlangen. Das Ziel ist es, die …

Elucidation of the mechanism of action for drug candidates is fundamental to drug
development, and it is strongly facilitated by metabolomics. Herein, we developed an …