Viscoelastic hemostatic assays: a primer on legacy and new generation devices

O Volod, CM Bunch, N Zackariya, EE Moore… - Journal of Clinical …, 2022 - mdpi.com
Viscoelastic hemostatic assay (VHAs) are whole blood point-of-care tests that have become
an essential method for assaying hemostatic competence in liver transplantation, cardiac …

Basic principles of viscoelastic testing

T Carll, GD Wool - Transfusion, 2020 - Wiley Online Library
Background Viscoelastic testing is a method of hemostatic analysis that provides a real‐
time, holistic view of ex vivo clotting. It allows for examination of both cellular and plasma …

Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19

JC Song, G Wang, W Zhang, Y Zhang, WQ Li… - Military Medical …, 2020 - Springer
Since December 2019, a novel type of coronavirus disease (COVID-19) in Wuhan led to an
outbreak throughout China and the rest of the world. To date, there have been more than …

[HTML][HTML] Viscoelastic testing: an illustrated review of technology and clinical applications

J Hartmann, D Hermelin, JH Levy - Research and Practice in Thrombosis …, 2023 - Elsevier
Viscoelastic testing (VET), including thromboelastography and thromboelastometry,
provides a rapid and comprehensive picture of whole blood coagulation dynamics and …

Point-of-care diagnostics in coagulation management

SD Sahli, J Rössler, DW Tscholl, JD Studt, DR Spahn… - Sensors, 2020 - mdpi.com
This review provides a comprehensive and up-to-date overview of point-of-care (POC)
devices most commonly used for coagulation analyses in the acute settings. Fast and …

SHock-INduced Endotheliopathy (SHINE): A mechanistic justification for viscoelastography-guided resuscitation of traumatic and non-traumatic shock

CM Bunch, E Chang, EE Moore, HB Moore… - Frontiers in …, 2023 - frontiersin.org
Irrespective of the reason for hypoperfusion, hypocoagulable and/or hyperfibrinolytic
hemostatic aberrancies afflict up to one-quarter of critically ill patients in shock. Intensivists …

The strengths and weaknesses of viscoelastic testing compared to traditional coagulation testing

T Cohen, T Haas, MM Cushing - Transfusion, 2020 - Wiley Online Library
Optimized acute bleeding management requires timely and reliable laboratory testing to
detect and diagnose coagulopathies and guide transfusion therapy. Conventional …

Thromboelastography-guided therapy enhances patient blood management in cirrhotic patients: a meta-analysis based on randomized controlled trials

J Hartmann, JD Dias, EG Pivalizza… - … in thrombosis and …, 2023 - thieme-connect.com
Patients with cirrhosis often have abnormal hemostasis, with increased risk of hemorrhage
and thrombosis. Thromboelastography provides a rapid assessment of the coagulation …

[HTML][HTML] A microfluidic hemostatic diagnostics platform: Harnessing coagulation-induced adaptive-bubble behavioral perception

L Chen, L Yu, M Chen, Y Liu, H Xu, F Wang, J Zhu… - Cell Reports …, 2023 - cell.com
Clinical viscoelastic hemostatic assays, which have been used for decades, rely on
measuring biomechanical responses to physical stimuli but face challenges related to high …

Viscoelastometry for detecting oral anticoagulants

P Groene, D Wagner, T Kammerer, L Kellert, A Giebl… - Thrombosis journal, 2021 - Springer
Background Determination of anticoagulant therapy is of pronounced interest in emergency
situations. However, routine tests do not provide sufficient insight. This study was performed …