The mechanisms of action of deep brain stimulation and ideas for the future development

K Udupa, R Chen - Progress in neurobiology, 2015 - Elsevier
Deep brain stimulation (DBS) has been used as a treatment of movement disorders such as
Parkinson's disease, dystonia, and essential tremor for over twenty years, and is a promising …

[HTML][HTML] Therapeutic update on Huntington's disease: symptomatic treatments and emerging disease-modifying therapies

D Dash, TA Mestre - Neurotherapeutics, 2020 - Elsevier
Huntington's disease (HD) is a monogenic neurodegenerative disorder that presents with
progressive motor, behavior, and cognitive symptoms leading to early disability and …

Movement disorders induced by deep brain stimulation

JF Baizabal-Carvallo, J Jankovic - Parkinsonism & related disorders, 2016 - Elsevier
Deep brain stimulation represents a major advance in the treatment of several types of
movement disorders. However, during stimulation new movement disorders may emerge …

Programming deep brain stimulation for tremor and dystonia: the Toronto Western Hospital algorithms

M Picillo, AM Lozano, N Kou, RP Munhoz, A Fasano - Brain stimulation, 2016 - Elsevier
Background Deep brain stimulation (DBS) is an effective treatment for essential tremor (ET)
and dystonia. After surgery, a number of extensive programming sessions are performed …

Subthalamic stimulation may inhibit the beneficial effects of levodopa on akinesia and gait

V Fleury, P Pollak, J Gere, G Tommasi… - Movement …, 2016 - Wiley Online Library
Background Gait and akinesia deterioration in PD patients during the immediate
postoperative period of DBS has been directly related to stimulation in the subthalamic …

Effect of deep brain stimulation on freezing of gait in patients with Parkinson's disease: a systematic review

A Razmkon, S Abdollahifard, E Taherifard… - British Journal of …, 2023 - Taylor & Francis
Background and objectives Freezing of gait (FOG) is a disabling gait disorder in patients
with Parkinson's disease (PD), characterized by recurrent episodes of halting steps …

[HTML][HTML] Deep brain stimulation in Huntington's disease—preliminary evidence on pathophysiology, efficacy and safety

L Wojtecki, SJ Groiss, CJ Hartmann, S Elben, S Omlor… - Brain sciences, 2016 - mdpi.com
Huntington's disease (HD) is one of the most disabling degenerative movement disorders,
as it not only affects the motor system but also leads to cognitive disabilities and psychiatric …

Low-frequency deep brain stimulation for movement disorders

JF Baizabal-Carvallo, M Alonso-Juarez - Parkinsonism & related disorders, 2016 - Elsevier
Introduction Traditionally, deep brain stimulation (DBS) for movement disorders (MDs) is
provided using stimulation frequencies equal to or above 100 Hz. However, recent evidence …

[HTML][HTML] Bradykinesia and dystonia

G Paparella, A Guerra, S Galosi… - …, 2023 - frontierspartnerships.org
Background: Bradykinesia has been reported in patients with dystonia. Despite this, the
pathophysiological mechanisms of bradykinesia in dystonia remain largely unknown …

Structural connectivity of subthalamic nucleus stimulation for improving freezing of gait

JN Strelow, JC Baldermann… - Journal of …, 2022 - content.iospress.com
Background: Freezing of gait (FOG) is among the most common and disabling symptoms of
Parkinson's disease (PD). Studies show that deep brain stimulation (DBS) of the …