Abstract von Willebrand disease (VWD) is the most common inherited bleeding disorder.
The disorder is characterized by excessive mucocutaneous bleeding. The most common …

Guidelines Management of severe peri-operative bleeding: Guidelines from the European
Society of Anaesthesiology and Intensive Care

Inherited platelet disorders resulting from platelet function defects and a normal platelet
count cause a moderate or severe bleeding diathesis. Since the description of Glanzmann …

Background Careful assessment of bleeding history is the first step in the evaluation of
patients with mild/moderate bleeding disorders, and the use of a bleeding assessment tool …

This clinical review explored coagulopathy in severely bleeding patients after major surgery
(eg, cardiac surgery with cardiopulmonary bypass or CPB), serious trauma, and postpartum …

Over the last 100 years the role of platelets in hemostatic events and their production by
megakaryocytes have gradually been defined. Progressively, thrombocytopenia was …

Background The future bleeding risk, especially after hemostatic challenges, and thus the
requirement for hemostatic treatment in patients with mild-to-moderate bleeding disorders …

Recent studies have demonstrated that only 30% of patients referred for assessment of a
possible bleeding tendency will eventually be diagnosed with a mild bleeding disorder …

Congenital dysfibrinogenemia (CD) is caused by structural changes in fibrinogen that modify
its function. Diagnosis is based on discrepancy between decreased fibrinogen activity and …

Background Bleeding assessment tools are key screening tests used in the evaluation of
patients with suspected inherited bleeding disorders. The International Society on …