Biomarkers for posttraumatic epilepsy

A Pitkänen, T Paananen, J Kyyriäinen, SD Gupta… - Epilepsy & Behavior, 2021 - Elsevier
A biomarker is a characteristic that can be objectively measured as an indicator of normal
biologic processes, pathogenic processes, or responses to an exposure or intervention …

Analysis of miRNA signatures in CSF identifies upregulation of miR-21 and miR-146a/b in patients with multiple sclerosis and active lesions

M Muñoz-San Martín, G Reverter… - Journal of …, 2019 - Springer
Background MicroRNAs (miRNAs) have been reported as deregulated in active brain
lesions derived from patients with multiple sclerosis (MS). In there, these post-transcriptional …

Glial responses during epileptogenesis in Mus musculus point to potential therapeutic targets

G Kalozoumi, O Kel-Margoulis, E Vafiadaki… - PLoS …, 2018 - journals.plos.org
The Mesio-Temporal Lobe Epilepsy syndrome is the most common form of intractable
epilepsy. It is characterized by recurrence of focal seizures and is often associated with …

Promising candidate cerebrospinal fluid biomarkers of seizure disorder, infection, inflammation, tumor, and traumatic brain injury in pediatric patients

SH Kim, SA Chae - Clinical and Experimental Pediatrics, 2021 - pmc.ncbi.nlm.nih.gov
Cerebrospinal fluid (CSF) is a dynamic metabolically active body fluid that has many
important roles and is commonly analyzed in pediatric patients, mainly to diagnose central …

Electrical stimulation of the ventral hippocampal commissure delays experimental epilepsy and is associated with altered microRNA expression

LS Costard, V Neubert, MT Venø, J Su, J Kjems… - Brain stimulation, 2019 - Elsevier
Background Up to 80% of mesial temporal lobe epilepsy patients with hippocampal
sclerosis (mTLE-HS) are resistant to pharmacological treatment, often necessitating surgical …