Medial and orbital frontal cortex in decision-making and flexible behavior

MC Klein-Flügge, A Bongioanni, MFS Rushworth - Neuron, 2022 - cell.com
The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

Functional heterogeneity within rat orbitofrontal cortex in reward learning and decision making

A Izquierdo - Journal of Neuroscience, 2017 - Soc Neuroscience
Rat orbitofrontal cortex (OFC) is located in the dorsal bank of the rhinal sulcus, and is
divided into the medial orbital area, ventral orbital area, ventrolateral orbital area, lateral …

A distributed, hierarchical and recurrent framework for reward-based choice

LT Hunt, BY Hayden - Nature Reviews Neuroscience, 2017 - nature.com
Many accounts of reward-based choice argue for distinct component processes that are
serial and functionally localized. In this Opinion article, we argue for an alternative viewpoint …

Amygdala-cortical collaboration in reward learning and decision making

KM Wassum - Elife, 2022 - elifesciences.org
Adaptive reward-related decision making requires accurate prospective consideration of the
specific outcome of each option and its current desirability. These mental simulations are …

Basolateral amygdala to orbitofrontal cortex projections enable cue-triggered reward expectations

NT Lichtenberg, ZT Pennington, SM Holley… - Journal of …, 2017 - Soc Neuroscience
To make an appropriate decision, one must anticipate potential future rewarding events,
even when they are not readily observable. These expectations are generated by using …

The role of the orbitofrontal cortex in alcohol use, abuse, and dependence

DE Moorman - Progress in Neuro-Psychopharmacology and …, 2018 - Elsevier
One of the major functions of the orbitofrontal cortex (OFC) is to promote flexible motivated
behavior. It is no surprise, therefore, that recent work has demonstrated a prominent impact …

Autocorrelation structure at rest predicts value correlates of single neurons during reward-guided choice

SE Cavanagh, JD Wallis, SW Kennerley, LT Hunt - elife, 2016 - elifesciences.org
Correlates of value are routinely observed in the prefrontal cortex (PFC) during reward-
guided decision making. In previous work (Hunt et al., 2015), we argued that PFC correlates …

A bidirectional corticoamygdala circuit for the encoding and retrieval of detailed reward memories

AC Sias, AK Morse, S Wang, VY Greenfield… - Elife, 2021 - elifesciences.org
Adaptive reward-related decision making often requires accurate and detailed
representation of potential available rewards. Environmental reward-predictive stimuli can …

[HTML][HTML] Age of gray matters: Neuroprediction of recidivism

KA Kiehl, NE Anderson, E Aharoni, JM Maurer… - NeuroImage: Clinical, 2018 - Elsevier
Age is one of the best predictors of antisocial behavior. Risk models of recidivism often
combine chronological age with demographic, social and psychological features to aid in …

Back to basics: Making predictions in the orbitofrontal–amygdala circuit

MJ Sharpe, G Schoenbaum - Neurobiology of learning and memory, 2016 - Elsevier
Underlying many complex behaviors are simple learned associations that allow humans
and animals to anticipate the consequences of their actions. The orbitofrontal cortex and …