Disease pathways and novel therapeutic targets in hypertrophic cardiomyopathy
H Ashrafian, WJ McKenna, H Watkins - Circulation research, 2011 - Am Heart Assoc
As described in earlier reviews in this series on the molecular basis of hypertrophic
cardiomyopathy (HCM), HCM is one of the archetypal monogenic cardiovascular disorders …
cardiomyopathy (HCM), HCM is one of the archetypal monogenic cardiovascular disorders …
Cardiopulmonary exercise test in patients with hypertrophic cardiomyopathy: a systematic review and meta-analysis
A Bayonas-Ruiz, FM Munoz-Franco, V Ferrer… - Journal of clinical …, 2021 - mdpi.com
Background: Patients with chronic diseases frequently adapt their lifestyles to their functional
limitations. Functional capacity in Hypertrophic Cardiomyopathy (HCM) can be assessed by …
limitations. Functional capacity in Hypertrophic Cardiomyopathy (HCM) can be assessed by …
Role of global longitudinal strain in predicting outcomes in hypertrophic cardiomyopathy
H Liu, I Pozios, B Haileselassie, A Nowbar… - The American Journal of …, 2017 - Elsevier
Global longitudinal strain (GLS) is a sensitive indicator of global left ventricular function
particularly in those with normal ejection fraction. We examined the potential value of GLS in …
particularly in those with normal ejection fraction. We examined the potential value of GLS in …
[HTML][HTML] Expanding the indications for septal myectomy in patients with hypertrophic cardiomyopathy: results of operation in patients with latent obstruction
HV Schaff, JA Dearani, SR Ommen, P Sorajja… - The Journal of Thoracic …, 2012 - Elsevier
OBJECTIVE: Many patients with symptomatic hypertrophic cardiomyopathy have minimal left
ventricular outflow tract gradients, and there is uncertainty whether their limitation is due to …
ventricular outflow tract gradients, and there is uncertainty whether their limitation is due to …
Intertechnique agreement and interstudy reproducibility of strain and diastolic strain rate at 1.5 and 3 tesla: A comparison of feature‐tracking and tagging in patients …
A Singh, CD Steadman, JN Khan… - Journal of Magnetic …, 2015 - Wiley Online Library
Purpose To determine the interstudy reproducibility of myocardial strain and peak early‐
diastolic strain rate (PEDSR) measurement on cardiovascular magnetic resonance imaging …
diastolic strain rate (PEDSR) measurement on cardiovascular magnetic resonance imaging …
Global cardiac alterations detected by speckle-tracking echocardiography in Fabry disease: left ventricular, right ventricular, and left atrial dysfunction are common and …
DA Morris, D Blaschke, S Canaan-Kühl, A Krebs… - … International Journal of …, 2015 - Springer
The aim of this study was to test the hypothesis that in patients with Fabry disease, 2D
speckle-tracking echocardiography (2DSTE) could detect functional myocardial alterations …
speckle-tracking echocardiography (2DSTE) could detect functional myocardial alterations …
Prolonged left ventricular twist in cardiomyopathies: a potential link between systolic and diastolic dysfunction
G Pacileo, L Baldini, G Limongelli… - European Journal of …, 2011 - academic.oup.com
Aims Left ventricular (LV) twist and untwist play a major role in LV mechanics. We sought to
acquire new pathophysiological insights in cardiomyopathies (CM) studying LV twist …
acquire new pathophysiological insights in cardiomyopathies (CM) studying LV twist …
Systolic and diastolic myocardial mechanics in hypertrophic cardiomyopathy and their link to the extent of hypertrophy, replacement fibrosis and interstitial fibrosis
G Nucifora, D Muser, P Gianfagna, G Morocutti… - The international journal …, 2015 - Springer
Aim of the present study was to investigate the relations between myocardial mechanics and
the extent of hypertrophy and fibrosis in hypertrophic cardiomyopathy (HCM). Forty-five …
the extent of hypertrophy and fibrosis in hypertrophic cardiomyopathy (HCM). Forty-five …
Exercise response in hypertrophic cardiomyopathy: blunted left ventricular deformational and twisting reserve with altered systolic-diastolic coupling
C Soullier, P Obert, G Doucende, S Nottin… - Circulation …, 2012 - Am Heart Assoc
Background—Abnormal left ventricular (LV) deformational mechanics have been
demonstrated in patients with hypertrophic cardiomyopathy (HCM) at rest, but there is a lack …
demonstrated in patients with hypertrophic cardiomyopathy (HCM) at rest, but there is a lack …
Quantification of left ventricular torsion and diastolic recoil using cardiovascular magnetic resonance myocardial feature tracking
Objectives Cardiovascular magnetic resonance feature tracking (CMR-FT) offers
quantification of myocardial deformation from routine cine images. However, data using …
quantification of myocardial deformation from routine cine images. However, data using …