Astrocytes are specialized non-neuronal glial cells of the central nervous system,
contributing to neuronal excitability and synaptic transmission (gliotransmission). Astrocytes …

Generalized epilepsy affects 24 million people globally; at least 25% of cases remain
medically refractory. The thalamus, with widespread connections throughout the brain, plays …

The electrographic hallmark of childhood absence epilepsy (CAE) and other idiopathic
forms of epilepsy are 2.5–4 Hz spike and wave discharges (SWDs) originating from …

Background: Absence seizures (petit mal seizures) are characterized by a brief loss of
consciousness without loss of postural tone. The disease is diagnosed by an …

Temporal lobe epilepsy (TLE) is the most common form of epilepsy in adults. Tissue
reorganization at the site of the epileptogenic focus is accompanied by changes in the …

Astrocytes and microglia are the main cell population besides neurons in the central
nervous system (CNS). Astrocytes support the neuronal network via maintenance of …

Epilepsy is a common disease in the central nervous system. There is growing evidence that
epilepsy is associated with glial cells, including astrocytes. Tumor necrosis factor α (TNFα) is …

Epilepsy is a chronic neurological disorder marked by recurrent seizures, significantly
impacting individuals worldwide. Current treatments are often ineffective for a third of …

Background Symptomatic epilepsy is a common symptom of glioblastoma, which may occur
in different stages of disease. There are discrepant reports on association between early …

Spike-wave discharges (SWDs) are EEG hallmarks of absence epilepsy, and they
spontaneously appear in adult WAG/Rij rats. SWDs are known to be vigilance-dependent …