Calcitonin gene-related peptide and its role in migraine pathophysiology

U Arulmani, A MaassenVanDenBrink… - European journal of …, 2004 - Elsevier
Migraine is a common neurological disorder that is associated with an increase in plasma
calcitonin gene-related peptide (CGRP) levels. CGRP, a neuropeptide released from …

CGRP and migraine: could PACAP play a role too?

EA Kaiser, AF Russo - Neuropeptides, 2013 - Elsevier
Migraine is a debilitating neurological disorder that affects about 12% of the population. In
the past decade, the role of the neuropeptide calcitonin gene-related peptide (CGRP) in …

[HTML][HTML] Epidermal nerve fibers modulate keratinocyte growth via neuropeptide signaling in an innervated skin model

D Roggenkamp, S Köpnick, F Stäb, H Wenck… - Journal of Investigative …, 2013 - Elsevier
Atopic eczema is a chronic inflammatory skin disease characterized by cutaneous nerve
fiber sprouting and epidermal hyperplasia, pointing to an involvement of the peripheral …

A novel diuretic hormone receptor in Drosophila: evidence for conservation of CGRP signaling

EC Johnson, OT Shafer, JS Trigg… - Journal of …, 2005 - journals.biologists.com
The Drosophila orphan G protein-coupled receptor encoded by CG17415 is related to
members of the calcitonin receptor-like receptor (CLR) family. In mammals, signaling from …

Effects and mechanisms of glucosides of chaenomeles speciosa on collagen-induced arthritis in rats

Q Chen, W Wei - International Immunopharmacology, 2003 - Elsevier
Effects of glucosides of chaenomeles speciosa (GCS)—a Chinese traditional herbal
medicine (CTM) on inflammatory and immune responses and its mechanisms in collagen …

Antiinflammatory activities of CGRP modulating innate immune responses in health and disease

B Holzmann - Current Protein and Peptide Science, 2013 - ingentaconnect.com
Sensory nerves are abundant in lymphoid organs and rapidly release the neuropeptide
calcitonin gene-related peptide (CGRP) in response to injury or infection. CGRP directly acts …

Modulation of immune responses by the neuropeptide CGRP

B Holzmann - Amino acids, 2013 - Springer
The peripheral nervous system is connected with lymphoid organs through sensory nerves
that mediate pain reflexes and may influence immune responses through the release of …

Gastric secretion

ML Schubert - Current opinion in gastroenterology, 2004 - journals.lww.com
An improved understanding of the pathways and mechanisms regulating gastric acid
secretion should lead to the development of novel therapies to prevent and treat acid-peptic …

RAMPs: the past, present and future

N Parameswaran, WS Spielman - Trends in biochemical sciences, 2006 - cell.com
The discovery of receptor-activity-modifying proteins (RAMPs) as accessory proteins
required for the appropriate localization and function of certain G-protein coupled receptors …

Structure–activity relationships for α‐calcitonin gene‐related peptide

HA Watkins, DL Rathbone, J Barwell… - British Journal of …, 2013 - Wiley Online Library
Calcitonin gene‐related peptide (CGRP) is a member of the calcitonin (CT) family of
peptides. It is a widely distributed neuropeptide implicated in conditions such as neurogenic …